Stem Cell Research Oversight

The University at Buffalo is committed to maintaining the highest ethical standards while permitting qualified investigators to engage in research using pluripotent human stem cells (pHSC). To assist with the process, UB and Roswell Park Comprehensive Cancer Center created a Stem Cell Research Oversight (SCRO) Committee.

On this page:

Committee Responsibilities

The committee reviews and approves research and training materials related to the derivation and use of pHSCs, including human embryonic stem cells (hESC) and pluripotent stem cells produced from non-embryonic human sources.

If you plan to use or derive pHSCs, including induced pluripotent stem cells, please contact the SCRO office.

Pluripotent Human Stem Cell Research Guidelines

These guidelines apply to any research or training use of pHSC. Pluripotent Human Stem Cell research is research involving any culture-derived, human pluripotent stem cell population that can:

  1. Sustain propagation in culture; and
  2. Self-renew to produce daughter cells capable of differentiation into mesoderm, ectoderm and endoderm.

This definition includes both embryonic and non-embryonic human stem cell lines regardless of the tissue of origin.

  • Induced pluripotent stem cells (iPSC)
  • Cells produced through somatic nuclear transfer (SCNT)
  • Altered Nuclear Transfer (ANT)

It does NOT include accepted medical treatment practices using adult stem cells, human cord blood or transplantation of non-pluripotential stem cells.

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