Microbiome Data Statistical Analysis

Recently with the increase in next generation sequencing, there is a growing number of experiments designed to study the microbiome. Researchers need a clear understanding of the statistical concepts required for the design, execution and interpretation of microbiome experiments.

We discuss taxonomic classification of bacterial sequences into organizational taxonomic units (OTUs). Then we discuss the statistical tests designed to assess abundance differences for OTUs across conditions. Lastly, this talk discusses the concepts of alpha and beta diversity across bacterial populations and provides visualization techniques for diversity metrics.

ACCREDITATION: The University at Buffalo Jacobs School of Medicine and Biomedical Sciences is accredited by the ACCME to provide continuing medical education for physicians.

CERTIFICATION: The University at Buffalo Jacobs School of Medicine and Biomedical Sciences designates this live activity for a maximum of 3.0 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CREDIT: This program is supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under award number UL1TR001412.