VICORA INC.

Novel clot removal device moves closer to market

Vicora, Inc., a Buffalo-based medical device startup, is developing an innovative catheter that enables interventional cardiologists and interventional radiologists to more effectively break up and remove difficult blood clots from the lungs and legs. The company has accelerated commercialization of this novel clot removal device with support from UB including incubator space, funding, clinical expertise and startup resources. Currently, Vicora is working to advance the technology toward FDA approval. 

Illustration of a human chest showing the heart highlighted in red, with an enlarged cross‑section of a coronary artery in the foreground containing a catheter and an expanded stent, representing cardiac angioplasty or coronary stent placement to restore blood flow.
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How Vicora collaborates with UB

CHALLENGE & OPPORTUNITY

Clogged catheters slow stroke treatment

To treat a vascular disease such as pulmonary embolisms and deep vein thrombosis, a thin catheter is threaded into the blood vessel to suction out the blood clot. However, the procedure is only effective in a fraction of cases because the catheter tip often becomes clogged by the clot. The clot can also break into smaller particles that travel throughout the patient’s circulatory system, causing additional risks and complications. Other device manufacturers have tried to solve for catheter deficiencies by increasing bore size or suction power but attempts to date have been either detrimental or insufficient. In a novel approach, Vicora is developing a new catheter equipped to help surgeons remove more of the clot to improve treatment and patient outcomes. 

Cardiac catheterization procedure. Stent angioplasty. 3d illustration.
Vicora vibrating catheter with Integrated Distal Tip Vibration.

SOLUTION & OUTCOME

Vibrating catheter tip disrupts and removes blood clots

Vicora has developed the world’s first catheter with an integrated distal tip that vibrates to break clots into finer specks, allowing more of the clot to be suctioned into the catheter and preventing clot fragments from circulating to other parts of the body. Vicora has filed several patents, obtained an exclusive worldwide supply agreement on the core technology, and is advancing through device development, test methods and animal testing at the Jacobs Institute and UB in preparation for FDA submission.

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