The goal of the Community of Scholars (COS) Seminar Series is to provide an opportunity for attendees to learn about topics addressing health disparities and clinical and translational research, which are central components of our Clinical and Translational Science Award (CTSA). Attendees from all disciplines including medicine, nursing, dentistry, public health, and pharmacy are invited to attend.
Chief, Division of Hematology/Oncology/BMT Nationwide Children’s Hospital Columbus, OH
Dr. Cripe will review advances in cancer immunotherapies highlighting bispecific diabodies and antibodies and chimeric antigen receptor (CAR) T cells. He will also briefly review the field of AAV gene therapy for congenital genetic disorders, and then describe how the challenges of cancer immunotherapies can be addressed using AAV gene therapy technologies to achieve off-the-shelf therapies providing long-term therapeutic effects. In addition, he will describe his work to apply these technologies to target circulating tumor cells to prevent the development of metastases from solid tumors.