Translational Pilot Studies Request For Proposals

Requests For Proposals (RFPs) are intended to solicit applications for projects that accomplish several goals. They should:

  • allow clinical-translational researchers to generate preliminary data to support the submission of federal and/or private research grant applications
  • seek to improve clinical research design, biostatistics, clinical research ethics, informatics, or regulatory pathways, and/or
  • support the design, development and/or validation of novel, clinically applicable devices, biomarkers, or analytical methods, or other avenues (defined by the applicant) that will substantially advance clinical and translational research.


The review process is structured to encourage investigators to submit innovative ideas and for reviewers to identify and reward innovation. Applications are scored on the basis of criteria outlined in the RFPs:

  1. scientific merit and innovation
  2. significance and impact on the field
  3. impact on research on special populations, people across the lifespan and underserved populations
  4. potential for reducing regional health care disparities
  5. effective use of a team science approach
  6. rationale and utilization of proposed budget
  7. potential that the study outcomes will lead to extramural funding.

No clinical trials beyond phase IIA will be supported by the program. Priority is given to applications that pair junior and established investigators and to projects that address health care disparities in underserved or underrepresented populations in Western New York.

Spring 2024 Translational Pilot Studies Request for Proposals (RFP) Timeline

Letters of intent due Monday, May 13, 2024, by 9:00 a.m.
Notification to applicants Early June 2024
Full proposals due Friday, July 26, 2024, by 5:00 p.m.
Notification to applicants Early-November 2024
Funding start date January 1, 2025

A Zoom information session on tips for success in obtaining CTSI Pilot Studies funding will be held at 10 a.m. on Monday, May 6. Click here to register