Looking for a hands-on experimentalist to reveal the physical underpinnings of biocatalysis. Curious molecular biologists to engineering physicists welcome!
Proteins are the machines of life, however the role of their unique structures in biological function is still not understood. In this project we will determine how enzyme structural dynamics contribute to substrate binding. Students will grow and characterize protein crystals using the newly patented method, anisotropic terahertz microscopy. Through these studies we will map out the vibrations for free and inhibitor bound lysozyme.
Results will be presented at professional conferences (i.e., American Physical Society, American Chemical Society, Biophysical Society, etc.) as either a poster or oral presentation. Students are encouraged to write a senior thesis based on their research for graduation with honors designation. Previous undergraduates have published their work in peer reviewed journals.
|Length of commitment||More than one year|
|Start time||Beginning of semester or winter/summer sessions|
|In-person, remote, or hybrid? ||In-person|
|Level of collaboration||Small group project (2-3 students) |
|Benefits||Research experience; academic credit|
|Who is eligible||Undergraduates who have taken first-year biology and physics|
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