Responses to Targeted Therapy in Acute Myeloid Leukemia

Stylized micrograph of peripheral blood smear from a patient with hypereosinophilia while receiving FLT3 inhibitor treatment.

Physician-scientist laboratory seeking students interested in translational research in blood cancers.

Project is Not Currently Available

This project has reached full capacity for the current term. Please check back next semester for updates.

Project description

Our lab studies cell signaling and epigenetic pathways in an aggressive form of bone marrow cancer called acute myeloid leukemia (AML). Our primary focus is on a subtype of AML with mutations in FLT3, which confer a worse prognosis. FLT3 inhibitors are effective, but not curative in FLT3 mutated AML. The overall goal of the lab is to develop better therapies to improve patient outcomes. We use techniques in molecular biology, flow cytometry, cell culture, and mouse models. 

Project outcome

The specific outcomes of this project will be identified by the faculty mentor at the beginning of your collaboration. 

Project details

Timing, eligibility and other details
Length of commitment To be determined by the student/mentor 
Start time Fall (August/September)
Spring (January/February)
Summer (May/June)
In-person, remote, or hybrid? In-Person Project
Level of collaboration Individual student project 
Benefits Academic credit 
Who is eligible All undergraduate students 

Project mentor

Pamela Sung

Assistant Professor

Roswell Park - Cancer Sciences

Phone: (716) 845-7739

Email: pamela.sung@roswellpark.org

Start the project

  1. Email the project mentor using the contact information above to express your interest and get approval to work on the project. (Here are helpful tips on how to contact a project mentor.)
  2. After you receive approval from the mentor to start this project, click the button to start the digital badge. (Learn more about ELN's digital badge options.) 
Start the Digital Badge

Preparation activities

Once you begin the digital badge series, you will have access to all the necessary activities and instructions. Your mentor has indicated they would like you to also complete the specific preparation activities below. Please reference this when you get to Step 2 of the Preparation Phase. 

The specific preparation activities for this project will be customized through discussions between you and your project mentor. Please be sure to ask them for the instructions to complete the required preparation activities.

Keywords

Cancer, Pharmacology, Therapeutics, Roswell