Build ultrafilter modules and apply chemistry and microbiology knowledge to explore emerging research questions related to virology in wastewater.
Wastewater-based virus surveillance is an effective way to monitor viral diseases at a community. Because infected individuals may shed viruses in their feces and/or urine, wastewater is a reservoir of different viruses, such as SARS-CoV-2, hepatitis A virus, and norovirus. While molecular methods, such as polymerase chain reaction (PCR) and genomic sequencing, are extremely sensitive to analyze viruses by detecting or sequencing their DNA/RNA, inhibitors present in the wastewater matrices can severely affect the sensitivity and accuracy of these assays. This project will primarily focus on the optimization of wastewater processing methods to generate high-concentration and high-quality viral DNA/RNA for downstream molecular analysis.
This project will contribute standard methods for detecting and sequencing viruses in wastewater, and the developed method will make an impact on viral disease prediction and prevention through wastewater-based epidemiology. At the end of the project, students can produce a research poster or presentation to synthesize their contributions.
|Length of commitment||About a semester (3-5 months)|
|In-person, remote, or hybrid?||In-person|
|Level of collaboration||Undergraduate students will work with a graduate student mentor |
|Benefits||Academic credit; work study; Honors credit|
|Who is eligible ||Juniors and seniors|
Once you begin the digital badge series, you will have access to all the necessary activities and instructions. Your mentor has indicated they would like you to also complete the specific preparation activities below. Please reference this when you get to Step 2 of the Preparation Phase.
Civil, Structural and Environmental Engineering