Can complement be modulated to stop disease in its tracks?
We are studying the role of the complement system in kidneys and brains during health and disease. Traditionally, major complement proteins were shown to be generated by the liver and are functional in the serum. Very recently, work from our lab and others have shown that complement proteins are also generated by other tissues/cells. We are studying the role of complement proteins in these new locations. This is very important since complement is being included as a therapeutic in different diseases.
Students will work on projects that will give them insights into role of complement in brain and kidney in different settings.
They will present the data obtained at meetings as posters and talks, and when the data is used in publications the students will be co-authors of the manuscripts.
|Length of commitment||Longer than a semester (about 6-9 months)|
|Start time||Spring 2022 (February)|
|In-person, hybrid, or remote?||In-person project|
|Level of collaboration||Small group project (2-3 students) |
|Benefits||Research experience; academic credit; possible stipend|
|Who is eligible||All undergraduate students|
8030D Clinical and Translational Research Center (CTRC) - 875 Ellicott St. (Downtown Buffalo)
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