Neurogenetic Substrates of Cocaine Addiction

Self-administration involves training a rat to respond for intravenous drugs like cocaine. .

Self-administration involves training a rat to respond for intravenous drugs like cocaine.

Seeking students to join research utilizing behavioral, genetic, and vivo neurophysiological techniques to study neural connections with reward-related brain areas associated with drug-taking behavior.

Project description

Drug use and addiction have enormous impact on our society. About 9% of the adult US population has used illicit drugs in the past month; lifetime use of illicit drugs is 47%; the majority of which included illicit drugs besides marijuana. In the case of alcohol and nicotine, 18% of Americans have abused alcohol, and as many of 80% of these people are regular smokers. Despite this, what is striking is that while many individuals are exposed to addictive drugs in their lifetimes, only a small percentage develop the patterns of drug-taking associated with addiction. These individuals are likely to be predisposed to addiction for distinct reasons, and determining what these predispositions are is a major goal of our laboratory. We are currently focused on how the response to drug-associated stimuli ("cues") drives motivated behavior and results in drug-taking behavior, and how genetic and environmental factors interact to influence the magnitude of these differences. To this end, our laboratory specializes in behavioral, genetic, and in vivo neurophysiological techniques to study neural connections within reward-related brain areas.

Project outcome

The specific outcomes of this project will be identified by the faculty mentor at the beginning of your collaboration. 

Project details

Timing, eligibility and other details
Length of commitment Year-long
Start time Fall
Level of collaboration Small group project
Benefits Academic Credit, Salary/Stipend, Voluntary Experience, Work Experience
Who is eligible Experience working with animals is required
Support Funding is available after the completion of the preparation badge. See below.

Project mentor

Paul Meyer

Associate Professor

Psychology

B71 Park Hall, North Campus

Phone: (716) 645-0263

Email: pmeyer@buffalo.edu

Preparation

To engage with this project, you will work through a series of Project-Based Collaboration digital badges to guide your experience. These badges will:

  1. Guide you in setting your goals and intentions as well as gaining additional context,
  2. Enhance your collaboration with your mentor/partner,
  3. Support your reflection and help you integrate your learning with your academic and professional goals.

All students who wish to participate in a project on the Project Portal must first complete the Project Preparation Digital Badge. First, contact the project mentor to discuss availability and after you’ve received approval, you can start the Project Preparation Digital Badge.

Preparation guidance

Once you have registered for the Project Preparation Digital Badge, you will receive further instructions related to the activities you will need to complete. In addition, you will also complete the following preparation activities for this particular project:

  • attending workshops or orientations (i.e., lab safety)
  • handling animals (rats)  
  • processing data 
  • attending lab meetings, participation in journal clubs 
  • assisting with experimental preparation 
  • assisting with surgical procedures