Effects of High Intensity Interval Training on Brain Signaling


How does a daily high intensity interval training regimen impact brain signaling?

Project description

The project seeks to examine the effects of exercise (chronic high intensity interval training) versus a sedentary environment on brain signaling. Using a rat model of exercise we seek to examine the effects of exercise on brain signaling using in vitro autoradiography methods. The project entails learning how to perform image analysis on the images of neurochemical binding in the brain. Data from this study will have important implications in understanding the mechanism of how exercise may have therapeutic potential in a variety of diseases.

Project outcome

Project outcomes include a poster and manuscript. Students will prepare a draft of both and help with editing these deliverables.

Project details

Timing, eligibility and other details
Length of commitment Year-long (10-12 months)
Start time
Fall (August/September)
Spring (January/February)
Summer (May/June)
In-person, remote, or hybrid? Hybrid Project
Level of collaboration Small group project (2-3 students)
Benefits Research experience
Who is eligible Freshmen, Sophmores and Juniors

Project mentor

Panayotis Thanos

Senior Research Scientist

Pharmacology and Toxicology

Phone: (716) 881-7520

Email: thanos@buffalo.edu

Start the project

  1. Email the project mentor using the contact information above to express your interest and get approval to work on the project. (Here are helpful tips on how to contact a project mentor.)
  2. After you receive approval from the mentor to start this project, click the button to start the digital badge. (Learn more about ELN's digital badge options.) 

Preparation activities

Once you begin the digital badge series, you will have access to all the necessary activities and instructions. Your mentor has indicated they would like you to also complete the specific preparation activities below. Please reference this when you get to Step 2 of the Preparation Phase. 

Please read the following 7 articles found in the link below.


Copy and paste this in your browser. You will then need to obtain the full text of these articles (PDF) from the UB library.




Pharmacology and Toxicology