The Clinical and Translational Science Award-linked KL2 Mentored
Career Development Award (MCDA) Program offers research mentoring,
career and professional development and funding to outstanding
junior faculty and senior fellows transitioning to independent
This mentored career development award is funded through the
National Center for Advancing Translational Sciences of the
National Institutes of Health under award number KL2TR001413 to the
University at Buffalo.
The KL2 MCDA engages talented, motivated scholars from different
health science and clinical disciplines (e.g., medicine, pharmacy,
nursing, public health, dental, bioengineering and others) to join
the clinical and translational science workforce to develop new
treatments for diseases and health disparities affecting our
The KL2 MCDA will provide research training and mentoring in
clinical and translational science to outstanding junior faculty in
health science disciplines. Specifically, the KL2 MCDA program
- Develop Scholars’ professional skills and facilitate a
seamless transition to their next career level within the clinical
and translational workforce pipeline, and
- Guide Scholars, enabling them to mentor students and peers in
our community, the region and nation.
Each Scholar will receive support to cover partial salary (up to
$75,000 plus fringe benefits per year towards 75 percent protected
time) and research, tuition and travel costs ($25,000/year) for up
to two years. Scholars will be required to apply for individual K
awards or equivalent mentored awards, or appropriate R type awards
soon after admission into the program.
Note: These guidelines follow the NIH instructions for
K-awards applications, in order to facilitate transition from the
Scholar award to other individual NIH K-awards. Please refer to the
FOA for K01, K08, K23 or others as apply to your research and
career goals, for recommended content on career development plans,
letters of support, research plans and other parts of the
Scholars participate in program activities to enhance their
research skills as well as career and professional development over
a two-year period.
- Mentored Research
- Mentoring Workshop Series
- Advanced K to R Grant Writing Workshop Series
- Professional Development Workshops
- Community of Scholars (COS)
- Opportunity to complete certificates in clinical and
translational sciences and/or master's and PhD degrees
- Applicants must define and conduct a clinical or translational
- Applicants must identify a multidisciplinary mentoring team
with extensive clinical and/or translational research experience
where one of the members is willing to serve as the primary
- The primary research mentor(s) should have sufficient
independent research support in an area related to the
Scholar’s research proposal to cover the costs of the
proposed research project that exceed the Scholar research funds
provided by the award. Should mentor(s) not have sufficient funding
in research grants and/or is awaiting award of a competitive
renewal, a letter of support from the department chair or school
dean committing to cover the difference in excess costs will be
- Applicants must commit 75 percent (nine calendar months) of
full-time effort on research activities and career development
activities associated with the KL2 MCDA. The remaining three months
effort can be divided among research, clinical and teaching
activities consistent with the proposed goals of the KL2 Mentored
Career Development Award.
Note: Scholars in certain clinical specialties (e.g.,
surgery) may commit less than 75 percent effort (but no less than
50 percent effort) if sufficiently justified by the need to
maintain critical clinical skills. Salary support will be prorated
Preference for funding will be given to outstanding
applicants bringing novel approaches towards reducing health
disparities in clinical populations and/or applicants with
experiences and/or attributes aimed at increasing diversity in the
clinical and translational workforce. This includes but is not
- having lived or worked in diverse and/or socioeconomically
- overcoming physical impairments,
- bringing new and alternative perspectives and approaches to
increase educational outcomes and excellence in clinical and
translational science, and/or
- being a member of a group traditionally underrepresented in
1. Letter of Intent: The Letter of Intent (LOI) must include the
following items (one page, biosketches not included):
- Name of Applicant and affiliation (attach new NIH-style
- Name of Primary Research Mentor and affiliation (attach new
- Title of mentored award research project
- Career development award goals (numbered, with brief
- Research project: overall hypothesis, specific aims and
relevance to health disparities
- Signed Eligibility Statement: I attest that I comply with the
grant award eligibility conditions described under C4a-d (not
included in page limit)
2. Complete Full Application Components
Applications must be assembled in the order described below,
compliant with stated page limits, and submitted in a single PDF
- Cover Page: Include the name of the applicant, title of
proposal, names of primary research mentors and a list of all
individuals providing letters of support (e.g.: research mentor,
quantitative mentor, other mentors, department chairs, institute
directors, etc.). Cover letter must be endorsed by the
applicant’s Department Chair/School Dean.
- NIH Biosketch: A new NIH-style biosketch must be provided
including a section on “Other Support,” outlining both
past and present other support.
- Proof of US citizenship or permanent residency.
- Transcript documenting degree.
- Candidate Information and Goals for Career Development:
(maximum four to six pages) Arial 11-point font with 0.5 inch
margins (left, right, top and bottom). State reasons for pursuing a
career in clinical and translational research. Describe background,
interests and experiences that prepare the candidate for the award;
specific plans and time line for meeting educational and career
development goals during the award; plans to interact with mentors;
how the research project and career/educational plan will
facilitate overall longer term career development goals. Complete
the Individual Development Plan (IDP), which is a useful tool to
stay on course towards achieving your career development goals and
to focus discussions with your mentors.
- Research Plan: Arial 11-point font with 0.5 inch margins (left,
right, top and bottom). The research should be designed to be
completed within the two-year time of the award. The work is
expected to generate sufficient data to allow the MCDA award
recipient to submit an externally funded career development or
independent research project award application.
- Research Abstract: (one page). Summarize the research project
and career development goals.
- Research Strategy:
- Specific Aims, including hypotheses and significance (one
- Research Plan (six pages)
- Background, significance and innovation
- Preliminary Studies (if available):
- Research Design and Methods (including strengths and
limitations of the approach)
- Training in Responsible Conduct of Research (one page)
- Human Subjects (not included in page limit)
Note: Although the IRB protocol can be listed as pending, no
research funds will be released until the full IRB for your study
- Vertebrate Subjects (not included in page limit)
Note: Although the IACUC protocol can be listed as pending, no
research funds will be released until the full IACUC for your study
- Literature Cited (not included in page limit).
- Diversity Statement (one page): Include statement(s) indicating
planned efforts to increase workforce diversity and inclusion,
excellence in educational outcomes and in translational and
clinical research and/or in bringing new perspectives and
experiences to accelerate research to reduce health disparities
- Budget: A separate budget for each of the two years
detailing your research expenses, using the budget form provided.
The budget form and instructions will be made available to those
applicants selected to submit a full application.
- Budget Justification: Provide a budget justification explaining
in detail each item included in the budget.
- Current Grant Support: List all current sources of grant
support past, present and pending. Include total direct and
indirect cost for each year, total period of support, description
of scope of the grant your role in the project, etc.
- Timeline (maximum one page): timeline for research and career
development activity during two-year award period.
- The following letters are required:
- Letters of Commitment from:
- Current Research Mentor and Co-Mentors (if identified) and
their commitment to mentoring and research support to the
candidate. Please include new NIH-style biosketches.
- Collaborators, if any.
- Letters of Recommendation from two previous mentors.
The KL2 Mentored Career Development Award involves activities
intended to enhance professional development and networking;
facilitate attendance at research conferences; and enhance
Scholar’s skills as teachers and mentors of future
generations of scientists in clinical and translational
Programs for the Scholars will include activities such as:
- Annual CTSI Forum: Participation in organization,
program development and invitation of keynote speakers.
- Community of Scholars: Collegial body which was formed
to provide junior scientists an opportunity to participate
regularly, grow academically and broaden their professional network
and get involved in community outreach activities. More
- Teaching and Mentoring: Participate in research teaching
and mentoring of high school, undergraduate, undergraduate summer
students and/or MD and PhD students.
- Outreach: Participate in outreach activities to enhance
and promote careers in science among K-12 students.