The Buffalo Glycoscience Symposium took place on January 23, 2020 at the Jacobs School of Medicine and Biomedical Sciences. The goal of this symposium was to stimulate discussions on how glycans may play a role in various biological contexts, help initiate collaborations that push the field, and also highlight local resources that are available to the community of scientists.
Buffalo Glycoscience Symposium
Jan 23rd 2020, 8:00am–1:30pm
Active Learning Center, 1st Floor
Jacobs School of Medicine and Biomedical Sciences, UB Downtown Campus
8:00-9:00 Check-in and breakfast
9:00-9:05 Welcome address: Ding Xu
Session 1: Translational Glycoscience
Chairs: Joseph Lau (Roswell Park) and Steve Free (UB-Biological Sciences)
9:05-9:30 Sriram Neelameghan & Ted Groth (UB)
Systems Glycobiology: Analysis of The Cancer Genome Atlas (TCGA) reveals changes in glycosylation pathways during cancer
9:30-9:55 Kate Rittenhouse-Olson (For-Robin, Inc)
Development of anti-TF-Ag antibody hJAA-F11 for clinical use in breast and lung cancer
9:55-10:20 Ryan Boniface (ThermoFisher)
Modification of glycans in bioprocessing
10:20-10:40 Rudiyanto Gunawan (UB)
Flux analysis of N-linked Glycosylation: An application to IgG production by CHO cell cultures
10:40-10:45 Conclusion and perspectives: J. Lau and S. Free
10:45-11:00 Coffee break
Session 2: Frontiers in Glycobiology
Chairs: Terry Connell (UB-Medical School) and Stefan Ruhl (Oral Biology)
11:00-11:25 Patrick Punch & Tianxin Yu (RPCCC, Lau lab)
Glycans and regulation of gastrointestinal epithelial homeostasis
11:25-11:40 Miaomiao Li (UB, Xu lab)
Essential Role of Heparan Sulfate–Osteoprotegerin Interaction in Bone Remodeling
11:40-11:55 Umesh Sharma (UB, Cardiovascular Medicine)
Galectin-3 at the Crossroads of Cardiovascular Inflammation and Fibrosis
11:55-12:10 Ben Cross (UB, Ruhl lab)
Sialic Acid Mediated Binding of Oral Streptococci to Neutrophilic Granulocytes
12:10-12:25 Pavan Patel (UB, Free Lab)
Characterizing the role of an α1,6-mannanase needed for Neurospora crassa cell wall biogenesis
12:25-12:30 Conclusion and perspectives: T. Connell and S. Ruhl
12:30-1:30 Working Lunch
Discussion leaders: Jennifer Surtees, Sriram Neelamegham: Creating resources for Glycoscience Research and Collaborative Science
Sponsors for this event included: UB Genome, Environment & Microbiome (GEM) Community of Excellence, UB School of Engineering & Applied Sciences, UB Department of Oral Biology, UB College of Arts and Sciences (CAS), UB Jacobs School of Medicine and Biomedical Sciences and The Roswell Park Cancer Institute