Crystals of the Month
Excited to feature a recent publication by HTX Center users in the Izard Lab at Scripps as Crystals of the Month!
‘We used over 1000 commercially available crystallization screens … to attempt to grow … crystals but our efforts were unsuccessful. Thus, we resorted to the high-throughput crystallization screening facility at the Hauptman-Woodward Medical Research Institute. Out of the 1536 crystallization conditions that were screened, crystals appeared from 500 mM imidazole (pH 6.5) and 15% (w/v) polyethylene glycol 3350 using the micro batch-under-oil method. We adapted this condition from the micro batch-under-oil method for hanging drop vapor diffusion … to grow crystals that diffracted X-ray beyond 1.6 Å Bragg spacings.‘
Check out the paper: https://doi.org/10.1016/j.mbplus.2021.100074
Crystals of the Month March 2021!
Celebrating the Crystals of the Month with nanolipoprotein crystallization from Megan Shelby and team at LLNL! Always great to see results from Crystallization Center users! Link to paper: https://mdpi.com/844698
Crystals of the Month February 2021!
Oak Ridge National Laboratory researchers Daniel Kneller, Andrey Kovalevsky & team have been at the heart of the fight against COVID-19. A gallery of structures of the heart-shaped main protease solved by the ORNL researchers, superimposed on flower-like crystals of the protein grown at the Crystallization Center.