The Exposome | Faculty Poster | 2017

MULTIPLE-METAL EXPOSURE, DIET, AND OXIDATIVE STRESS IN URUGUAYAN SCHOOL CHILDREN

Katarzyna Kordas, Aditi Roy, Marie Vahter, Nelly Mañay, Fabiana Peregalli, Jing Nie, Gabriela Martínez, Elena I. Queirolo5
Figure 1. Multi-metal association with urinary 8-isoprostane, by dietary intake strata.

Figure 1.  Multi-metal association with urinary 8-isoprostane, by dietary intake strata

Introduction

  • Oxidative stress (OS) is an important consequence of exposure to toxic metals.
  • It is unclear to what extent low-level exposure to multiple metals contributes to OS in young children.
  • There is little understanding of whether diet rich in antioxidant nutrients reduces metal-induced OS in children.

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Project Links

  • 9/25/19
    Childhood exposure to metals, pesticides and other neurotoxins can result in irreversible neuropsychological impairments. Whereas metal exposures have declined in the general U.S. population and significant progress has been made in the reduction of certain metals in the environment, other environmental exposures, like pesticides and air pollution, are continuing to be a problem. These exposures often occur in the context of low family resources, poor nutrition, or unsafe neighborhoods.