Center for Human Experimental Therapeutics

TPRC Lab

The University of Rochester Medical Center has established a Center for Human Experimental Therapeutics (CHET) whose mission is to conduct hypothesis-driven, rigorously designed, initial investigations of novel therapeutic interventions for human diseases. 

TPRC and CHET Collaboration: Bridging excellence between universities

TPRC is designed to foster collaboration and advance innovation at multiple stages of drug development, including:

  • Discovery
  • Pre-clinical evaluation
  • Phase I, II, and III FDA trials 
  • Ongoing post-approval Phase IV research
  • Nanomedicine

The core’s work is wide-ranging, but emphasizes:

  • Oncology
  • Neurology
  • Infectious disease 
  • Cardiovascular disease 
  • Inflammation and immunosuppression

Contributing to the development of new therapeutics, diagnostics and devices is a central goal of the program, which works with corporate partners to foster the goals of commercialization and regional economic development.

  • Core laboratory facility for bioanalysis and drug development
  • Healthcare informatics and medication management research network
  • Translational pharmacogenomics program incorporating in-vitro experimental therapeutic models 
  • International pharmacotherapy education and research initiative
  • Efficient system with industry-standard quality assurance and operating procedures
  • Data management and data analysis provided in conjunction with the Center for Computational Research
  • Links with facilities throughout the UB Clinical and Translational Research Center and National Center for Ontological Research