Kirk Personius Laboratory

The broad goal of the Kirk Personius Laboratory's reserach is to understand how communication between motor neurons and muscle fibers guides the development of the neuromuscular junction, and how this communication breaks-down following injury or disease. Current research focuses on improving the rate of reinnervation and reducing muscle atrophy after peripheral nerve injury. The goal of researchers in Personius' lab is to manipulate NANOG expression to expand the critical period for when functional reinnervation is possible.