Global Child | Student Poster | 2019

NEUROIMAGING GUIDED NON-INVASIVE BRAIN STIMULATION FOR A LOW-COST VR-BASED EXERGAMING PLATFORM

Zeynab Rezaee, Dhaval Solanki, Adyasha Dash2, M. V. Padma Srivastava, Uttama Lahiri, Anirban Dutta
Data Analysis: Optimization for leg area.

Introduction

About half of the stroke survivors are left with some degree of disability. Innovative methodologies for restorative neurorehabilitation are urgently required to reduce long-term disability. Neuroplasticity is involved in post-stroke functional disturbances, but also in rehabilitation. Cerebellar transcranial direct current stimulation (ctDCS) produces polarity specific effects by polarizing the Purkinje cells thereby affecting the activity in the deep cerebellar output nuclei. These effects on distant plasticity in human cortical areas (i.e., the motor cortex) are explainable by the cerebellar role in modulating sensory processing. Determination of the induced electric field during ctDCS is crucially important for a better understanding of the effects. Modeling studies have shown that the ctDCS electric field distribution reaches the human cerebellum where the posterior and the inferior parts of the cerebellum are particularly susceptible [1]. However, an objective lobular atlas-based analysis of subject-specific electric field distribution during ctDCS was not found in the published literature. CLOS pipeline can be leveraged to optimize electromagnetic stimulation to target cerebellar lobules related to different cognitive and motor functions.

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