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Multiple Sclerosis Research Innovation Fund

Students in Pharmacy class in Cooke Hall.

This fund supports clinical and translational research related to multiple sclerosis, which affects more than two million people worldwide.

At the School of Pharmacy and Pharmaceutical Sciences, our research into therapeutics for multiple sclerosis (MS) has helped lead to numerous discoveries — including a finding that that cholesterol affects the progression of the disease, an indication that MS progresses more rapidly in African American patients than in Caucasian patients, and more information about the mechanisms behind a regularly used treatment for MS. 

Our current work focuses on how the progression of this chronic, disabling neurological disease is affected by cholesterol and lipids, and by environmental and lifestyle factors such as smoking, vitamin D levels and immune responses to the Epstein-Barr virus — the common cause for mono.

By investigating the neuroimmunological and genomic mechanisms that contribute to clinical treatment responses, we strive to delineate the interactions among patient-specific, environmental and genetic factors that contribute to inter-individual differences in disease progression.

Our unique multi-disciplinary approach leverages our researchers’ strengths in pharmaceutical sciences and bioengineering, as well as productive collaborations with scientists from clinical disciplines.

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News from School of Pharmacy and Pharmaceutical Sciences

  • UB CIGBS Announces Stop Diabetes Progression, a New Global Community Health Site Initiative
    10/18/23
    The University at Buffalo (UB) Center for Integrated Global Biomedical Sciences (CIGBS) has announced plans to launch, Stop Diabetes Progression, a new health initiative, focusing on the creation of community-based education networks in Western New York, Jamaica and Zimbabwe to engage individuals with pre-diabetes and those with an established diagnosis of diabetes mellitus. The goal of this new initiative is to stop the progression of the disease for both groups.
  • UB faculty, staff receive SUNY Chancellor’s Awards
    6/7/23

    Twenty have been recognized for consistently superior professional achievement and the ongoing pursuit of excellence.

  • Can’t Be Grateful Enough
    8/2/22
    Mario Rocci Jr. (BS ’76, PhD ’81) wants others to receive the support he received at UB.
  • Sprowl receives NIDCD/NIH grant to study protein’s role in preventing drug-induced hearing loss
    6/5/23
    Jason Sprowl, PhD, assistant professor, Department of Pharmaceutical Sciences, has been awarded a $432,182 grant from National Institute on Deafness and Other Communication Disorders (NIDCD) and the National Institutes of Health (NIH). The study, called “Role of MCT6 in mediating cisplatin-induced ototoxicity,” will help researchers understand and prevent a prevalent type of drug-induced hearing loss in cancer patients.
  • UB SPPS hosts Ann E. Weber, PhD, as 2023 David Chu lecturer
    5/9/23
    On May 8, the University of Buffalo School of Pharmacy and Pharmaceutical Sciences (UB SPPS) welcomed Ann E. Weber, PhD, senior vice president, Research and Development, Kallyope Inc., as our 2023 David Chu Lecturer.
  • Qu receives NIH grant to develop targeted mass spectrometry assays as markers in monitoring Type 1 diabetes
    9/5/23
    Jun Qu, PhD, professor, Department of Pharmaceutical Sciences, has been awarded a four-year $982,617 U01 grant from the National Institutes of Health (NIH). The study, called “Robust Mass Spectrometric Protein/Peptide Assays for Type 1 Diabetes Clinical Applications,” will develop novel, highly sensitive assays that quantify proteins or peptide hormones to effectively monitor the progression or efficacy of new clinical interventions prior to or following the onset of Type 1 diabetes.
  • Fusco: Named a Fellow of the National Academies of Practice and recipient of AACP SOTL Grant
    4/11/23
    Nicholas Fusco, PharmD '10, division head, Division of Education and Teaching Innovation and clinical associate professor, Department of Pharmacy Practice, has been inducted as a Distinguished Fellow of the National Academies of Practice (NAP) and is a recipient of a 2023 American Association of Colleges of Pharmacy (AACP) Scholarship of Teaching and Learning Grant (SOTL).