Nanostructure Fabrication for Biosensing Applications

Dmitrii Kapitonov, Richard Samoilenko and Aidel Alshuaibee, Gregory Kaminski

Rise of opioid crisis and SERS active chip (AAO type).

Rise of opioid crisis and  SERS active chip (AAO type)

Undergraduate Student Project

Introduction

The recent surge in opioid addiction has led to what is known today as the opioid crisis. Synthetic opioids contribute to the majority of opioid overdoses. Fentanyl is one such synthetic opioid that is 50-100 times more potent than prescription opioids such as morphine. Current fentanyl sensing techniques are not accurate enough to prevent these deaths. Therefore, it is apparent that improved detection of fentanyl in both trace concentrations and within mixtures is necessary. The goal of our project is to produce a cost efficient nanostructure that can mass produced and provides maximum sensitivity for fentanyl detection.

Abstract

The most common of the synthetic opioids is fentanyl. The reason for the large spike in overdose deaths attributed to synthetic opioids is due to the presence of fentanyl in other opioids, such as heroin. The extreme potency of fentanyl leads drug dealers and others alike to add it to other drugs to achieve a better high. Current fentanyl sensing techniques are simply not accurate enough for the safety of the public. To combat the issue of synthetic opioid overdoses, most frequently due to fentanyl, the group tried to fabricate a SERS (surface-enhanced Raman spectroscopy) active nanostructure that follows certain key criteria: maximum sensitivity,  orientation for the mass production, portability.

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