Seeking students interested in understanding how signal transduction pathways regulate morphogenetic responses as relevant to human health, cancer and other diseases.
Our lab is interested in understanding how signal transduction pathways regulate morphogenetic responses. We study MAP kinase pathways in fungal species including the model genetic system budding yeast and human pathogen C. albicans. One focus of the lab is to understand how the polarity Rho-type GTPase Cdc42 is activated in the context of a specific MAP kinase pathway. Cdc42 and other proteins can function in multiple pathways. This is part of a general problem surrounding signaling pathways that control specific processes through networks of common or shared factors. How a specific output results from the activation of a common module is not clear and is a problem addressed by our lab. Understanding "signaling specificity" is relevant to human health because cross talk between pathways can lead to cancer and other diseases.
The specific outcomes of this project will be identified by the faculty mentor at the beginning of your collaboration.
|Length of commitment||To be determined by student/mentor|
|Start time||Spring, Summer|
|Level of collaboration||To be determined by student/mentor|
|Benefits||Academic Credit, Work Study|
|Who is eligible||A/B average; hard working, self-motivated|
Students participating in this project might be interested in and eligible for the Goldwater Scholarship and the National Science Foundation Graduate Research Fellowship. Connect with the Office of Fellowships and Scholarships to learn more.
The specific preparation activities for this project will be customized through discussions between you and your project mentor. Please be sure to ask them for the instructions to complete the required preparation activities.