Organic Chemistry for Therapeutic Innovation

IL2 protein model.

Research chemically modified IL2s for cancer immunotherapy.

Project description

Recombinant proteins have become an important class of biological therapies to treat a range of human diseases including cancer and diabetes. In effort to increase the capability of protein therapeutics, Dr. Lin's lab has been working on recombinant proteins containing novel chemical functionalities using a genetic code expansion strategy. This undergraduate research project seeks to develop covalent interleukin 2 (IL2) analogs that display selective IL2 receptor subunits for cancer immunotherapy applications.

Project outcome

Professional, presentation-ready poster or professional research report.

Project details

Timing, eligibility and other details
Length of commitment About 3-5 months
Start time Fall 2021
Level of collaboration Small group project (2-3 students)
Benefits Research experience; academic credit
Who is eligible Juniors and seniors who have taken CHE 201/202 or CHE 203/204

Project mentor

Qing Lin

Professor

Chemistry

Phone: (716) 645-4254

Email: qinglin@buffalo.edu

Start the project

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Preparation activities

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