Organic Chemistry for Therapeutic Innovation
Research chemically modified IL2s for cancer immunotherapy.
Project description
Recombinant proteins have become an important class of biological therapies to treat a range of human diseases including cancer and diabetes. In effort to increase the capability of protein therapeutics, Dr. Lin's lab has been working on recombinant proteins containing novel chemical functionalities using a genetic code expansion strategy. This undergraduate research project seeks to develop covalent interleukin 2 (IL2) analogs that display selective IL2 receptor subunits for cancer immunotherapy applications.
Project outcome
Professional, presentation-ready poster or professional research report.
Project details
| Length of commitment | About 3-5 months |
| Start time | Fall |
| In-person, remote, or hybrid? | In-person |
| Level of collaboration | Small group project (2-3 students) |
| Benefits | Research experience; academic credit |
| Who is eligible | Juniors and seniors who have taken CHE 201/202 or CHE 203/204 |
Project mentor
Qing Lin
Professor
Chemistry
Phone: (716) 645-4254
Email: qinglin@buffalo.edu
Start the project
- Email the project mentor using the contact information above to express your interest and get approval to work on the project. (Here are helpful tips on how to contact a project mentor.)
- After you receive approval from the mentor to start this project, click the button to start the digital badge. (Learn more about ELN's digital badge options.)
Preparation activities
Once you begin the digital badge series, you will have access to all the necessary activities and instructions. Your mentor has indicated they would like you to also complete the specific preparation activities below. Please reference this when you get to Step 2 of the Preparation Phase.
- Read A Smarter, Safter IL-2 to understand more about what this research project will focus on.
Keywords
Chemistry