Neurodegeneration in Blast-Induced Traumatic Brain Injury
This project investigates various neurotherapeutics for blast-induced traumatic brain injury.
Project description
Blast-induced traumatic brain injury, also known as shell shock or blast concussion, results in a variety of symptoms which often overlap with post-traumatic stress disorder. Brain Plasticity and Neurorehabilitation Laboratory at UB focuses on investigating the mechanism of vestibular and auditory neurodegeneration following blast overpressure of various impact levels and repetitions in pre-clinical animal models. You will have an opportunity to probe the mechanism of neurodegeneration in experimental animal models using any of the tools of molecular biology, histology or cell culture techniques.
Project outcome
The pathomechanism underlying neurological sequelae of blast induced traumatic brain injury will be identified. Further, therapeutic target will be identified and validated to develop a pharmacologic approach for bTBI.
Project details
| Length of commitment | About a semester (3-5 months) |
| Start time | Anytime |
| In-person, remote, or hybrid? | In-person |
| Level of collaboration | Individual student project |
| Benefits | Academic Credit, Volunteer |
| Who is eligible | Sophomores, Juniors, Seniors with ability to work independently and read related work |
Core partners
- Brain Plasticity and Neurorehabilitation Laboratory at UB
- Prof. Robert Burkand
- Dr. Supriya Mahajan
Project mentor
Vijaya Prakash Krishnan Murthaiah
Assistant Professor
Rehabilitation Sciences
Start the project
- Email the project mentor using the contact information above to express your interest and get approval to work on the project. (Here are helpful tips on how to contact a project mentor.)
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Preparation activities
The specific preparation activities for this project will be customized through discussions between you and your project mentor. Please be sure to ask them for the instructions to complete the required preparation activities.
Keywords
Rehabilitation Sciences