Neurodegeneration in Blast-Induced Traumatic Brain Injury

a man leans over a metal rehabilitation machine.

This project investigates various neurotherapeutics for blast-induced traumatic brain injury.

Project description

Blast-induced traumatic brain injury, also known as shell shock or blast concussion, results in a variety of symptoms which often overlap with post-traumatic stress disorder. Brain Plasticity and Neurorehabilitation Laboratory at UB focuses on investigating the mechanism of vestibular and auditory neurodegeneration following blast overpressure of various impact levels and repetitions in pre-clinical animal models. You will have an opportunity to probe the mechanism of neurodegeneration in experimental animal models using any of the tools of molecular biology, histology or cell culture techniques.

Project outcome

The pathomechanism underlying neurological sequelae of blast induced traumatic brain injury will be identified. Further, therapeutic target will be identified and validated to develop a pharmacologic approach for bTBI.

Project details

Timing, eligibility and other details
Length of commitment About a semester (3-5 months)
Start time Anytime
Level of collaboration Individual student project
Benefits Academic Credit, Volunteer
Who is eligible Sophomores, Juniors, Seniors with ability to work independently and read related work

Core partners

  • Brain Plasticity and Neurorehabilitation Laboratory at UB
  • Prof. Robert Burkand
  • Dr. Supriya Mahajan

Project mentor

Vijaya Prakash Krishnan Murthaiah

Assistant Professor

Rehabilitation Sciences

633 Kimball Tower

Phone: (716) 829-6290

Email: vijayapr@buffalo.edu

Start the project

  1. Email the project mentor using the contact information above to express your interest and get approval to work on the project. (Here are helpful tips on how to contact a project mentor.)
  2. After you receive approval from the mentor to start this project, click the button to start the digital badge. (Learn more about ELN's digital badge options.) 
Fulfilling Academic Major/Minor Requirements

If you are planning to use this project to satisfy program requirements for your academic major or minor, it is your responsibility to obtain approval from your academic department prior to beginning the project. 

Preparation activities

The specific preparation activities for this project will be customized through discussions between you and your project mentor. Please be sure to ask them for the instructions to complete the required preparation activities.