Our long-term research goal is to decipher the gene regulatory network that directs the embryonic palate development.
Cleft palate (CP) is caused by disruption of palatogenesis during embryonic development. Although surgery is a standard option to repair CP, patients often require additional surgeries, special dental care, and speech therapy as they get older. A more comprehensive understanding of palatogenesis will lead to development of better methods for diagnosis, treatment, and prevention of issues associated with CP. Despite extensive studies on palatogenesis, developmental gene regulation programs are poorly understood. This project aims to pioneer the gene regulatory network for palatogenesis. Our main experimental approaches involve cell/molecular biology, mouse genetics and genome-wide studies.
|Length of commitment||Year-long (10-12 months)|
|Level of collaboration||Individual student projects|
|Who is eligible||All undergraduate students|
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