Cytoskeleton and cell motility; Molecular Basis of Disease; Pulmonary Disease
My group is interested in applying advanced bio-fabrication technologies such as organ/organoid-on-chip models and 3D bioprinting to develop novel engineered tissue models for disease modeling, drug discovery and damaged tissue repair.
My clinical interests focus on understanding the mechanisms behind organ fibrosis and solid tumors and developing effective therapies for these conditions. For instance, we are working on engineered tumor organoid models to study stromal formation within the solid tumor microenvironment, examining how this stroma influences T-cell immunotherapy efficacy and glioblastoma invasion. Additionally, we are developing lung fibrosis-on-chip models to investigate the immune-epithelial-mesenchymal interactions that drive lung fibrosis formation.
