Postdoctoral Fellow, West Virginia University (2002)
MS, Chinese Academy of Preventive Medicine (1996)
MD, Anhui Medical University (1990)
Associate Professor, SUNY at Buffalo (2011-present)
Assistant Professor, State University of New York at Buffalo (2006-present)
Research Assistant Professor, Dept. of Microbiology, Immunology & Cell Biology, West Virginia University, School of Medicine (2003–2005)
Research Instructor, Microbiology, Immunology and Cell Biology, West Virginia University, School of Medicine (2002–2003)
Post Doctoral Fellow, West Virginia University, School of Medicine (1997–2002)
Bacterial genetics and Pathogenesis: My research is trying to understand the biology, genetics and pathogenesis of pathogenic spirochetes, including Borrelia burgdorferi (Lyme disease), oral Treponema denticola (periodontal infections), and Brachyspira species (swine dysentery and human diarrheal disease).
Oral Microbiology and Periodontal disease
Grants and Sponsored Research:
April 2012–March 2017 Amylase Binding and Gene Expression in S. gordonii. NIH-NIDCR Role: Co-Investigator $1,250,000
Li C, Xu H, Zhang K, Liang FT. Inactivation of a Putative Flagellar Motor Switch Protein FliG1 Prevents Borrelia burgdorferi from Swimming in Highly Viscous Media and Blocks its Infectivity. Molec Microbiol. 2010; 75(6).
Sal MS, Li C, Motaleb MA, Shibata S, Aizawa S, Charon NW. Borrelia burgdorferi Uniquely Regulates Its Motility Genes and Has An Intricate Flagellar Hook-Basal Body Structure. J Bacteriol. 2008; 190.
Li C, Wolgemuth CW, Marko M, Morgan DG, Charon NW. Genetic Analysis of Spirochete Flagellin Proteins and Their Involvement in Motility, Filament Assembly, and Flagella Morphology.. J Bacteriol. 2008; 190(16).
Motaleb MA, Miller MR, Bakker RG, Li C, Charon NW. Isolation and Characterization of Chemotaxis Mutants of the Lyme Disease Spirochete Borrelia burgdorferi Using Allelic Exchange Mutagenesis, Flow Cytometry, and Cell Tracking. Methods Enzymol. 2007; 422.
Motaleb MA, Miller MR, Li C, Charon NW. Phosphorylation Assays of Chemotaxis Two-Component System Proteins in Borrelia burgdorferi. Methods Enzymol. 2007; 422.
Bakker RG, Li C, Miller MR, Cunningham C, Charon NW. Identification of Specific Chemoattractants and Complementation of cheA2 of Borrelia burgdorferi: A Flow Cytometry-Based Capillary Tube Chemotaxis Assay. Appl Environ Microbiol. 2006; 73.
Motaleb MA, Miller MR, Li C, Bakker RG, Goldstein SF, Silversmith RE, Bourret RB, Charon NW. CheX is a CheY-P Phosphatase Essential for Borrelia burgdorferi Chemotaxis. J Bacteriol. 2005; 187.
Zuerner RL, Stanton TB, Miniton FC, Li C, Charon NW, Trott DJ, Hampson DJ. Genetic Variation in Brachyspira: Chromosomal Rearrangements and Sequence Drift Distinguish B. pilosicoli from B. hyodysenteriae. Anaerobe. 2004; 10.
School of Dental Medicine Student Research and Honors Committee; Member (2007)
Oral Biology, School of Dental Medicine Graduate Committee, Preliminary Exams; Member (2006)
School of Dental Medicine Infection Control/Biohazard Committee; Member (2006)
School of Dental Medicine Thesis Advisory Committee; Member (2006)
the MRBSB Faculty Advisory Committee; Molecular Recognition in Biological Systems and Bioinformatics' (MRBSB) focus centers on research done on every level of a given biological system, whether it is chemical, molecular, genetic, cellular, tissue, organ or whole organ systems.
Bringing together researchers from the School of Medicine and Biomedical Sciences; the School of Engineering and Applied Sciences; the New York State Center of Excellence in Bioinformatics and Life Sciences; Roswell Park Cancer Institute and several departments within the College of Arts and Sciences, MRBSB looks at biological systems at the cross-section between chemistry and biology.; Committee Member (2010)
Dental School Dean Search Committee; Recruiting new dean of Dental School of Medicine, SUNY at Buffalo; Committee Member (2009)
IGPBS Admissions Committee; Committee Member (2008–2011)
Student Research & Honors Committee; Committee Member (2007)
Infection and Biohazard Control Committee; Committee Member (2006–2009)