Publications and Grants

Publications.

Let us take a glimpse of the publications and grants by our Faculty and students

Publications 2019

1. Clark, B.S., G.L. Stein-O'Brien, F.Shiau, G. H. Cannon, E. Davis-Marciasak, T.S Sherman, C.P.Santiago, T.V.Hoang, F.Rajaii, R. E. James-Esposito, R. M. Gronostajski, E. J. Fertig, L. A. Goff, and S. Blackshaw. Single-Cell RNA-Seq Analysis of Retinal Develpment Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification. Neuron (2019) PMID: 31128945

2. Fraser, J., A. Essebier, A.S. Brown, R.A. Davila, A. S. Sengar, Y. Tu, K. S. Ensbey, B. W. Day, M.P. Scott, R. M. Gronostajski, B. J. Wainwright, M. Boden, T. J. Harvey, and M. Piper. Granule neuron precursor cell proliferation is regulated by NFIX and intersectin 1 during postnatal cerebellar development. Brain Struct Funct 224 (2019) 811-27. PMID: 30511336

3. Piper, M., R. Gronostajski, and G. Messina, Nuclear Factor One X in Development and Disease. Trends Cell Biol. 29 (2019) 20-30. PMID: 30287093

4. Zenker, M., J. Bunt, I. Schanze DSchanze, M. Piper, M. Priolo, E. H. Gerkes, R. M. Gronostajski, L. J. Richards, J. Vogt, M. W. Wessels, and R. C. Hennekam. Variants in nuclear factor I genes influence growth and development. Am J Med Genet C Semin Med Genet (2019) PMID: 317302571

5. Fraser, J., A. Essebier, A. S. Brown, R. A. Davila, D. Harkins, O. Zalucki, L. P. Shapiro, P. Penzes, B. J. Wainwright, M. P. Scott, R. M. Gronostajski, M. Boden, M. Piper, and T. J. Harvey. Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development. Cerebellum (2019) PMID: 31838646

6. M.A. Mohamed, A. Fallahi, A.M.A. El-Sokkary, S. Salehif, M.A. Aklb, H. Fenniri, A. Tamayol*, A. Khademhosseini*, S.T. Andreadis*, C. Cheng* (2019). Stimuli-Responsive Biomimetic Scaffolds for Tissue Engineering Applications: From Chemistry to Biofabrication Technology. Progress in Polymer Science 98: 101147 (* co-corresponding authors).

7. M. Beitelshees, A. Hill, Y. Li, M. Chen, M.K. Ahmadi, R. J. Smith Jr, S.T. Andreadis, P. Rostami, C.H. Jones, B.A. Pfeifer. (2019). Antigen delivery format variation and formulation stability through use of a hybrid vector. Vaccine X. 1:100012

8. S.M. Boroujeni, A. Kunson, P. Mehrotra, G. Tseropoulos, M.E. Bronner, S.T. Andreadis (2019). Neural crest stem cells from human epidermis of aged donors maintain their multipotency in vitro and in vivo. Scientific Reports 9(1): 9750

9. K. Nam, S.M. Dean, C.T. Brown, C.-S. Wang, P. Lei, S.T. Andreadis* and O.J. Baker* (2019). Synergistic Effects of laminin peptides, VEGF and FGF9 on Salivary Gland Regeneration. Acta Biomaterialia 91: 186-194 (* co-corresponding authors) 

10. R.J. Smith Jr., T. Yi, B. Nasiri, C.K. Breuer, S.T. Andreadis (2019). Implantation of VEGF-functionalized vascular grafts: regenerative and immunological response. FASEB J. 33(4): 5089-5100

11. Y. Liu, P. Lei, S. Row, S.T. Andreadis (2019). Cadherin-11 enhances cell proliferation and tissue regeneration via the PDGFR-Akt Signaling Axis . FASEB J

12. Malhotra S, Canty J. Structural and Physiological Imaging to Predict the Risk of Lethal Ventricular Arrhythmias and Sudden Death. JACC Cardiovascular Imaging. 2019; 2049(2064).

13. Suzuki G, Weil BR, Young, Rebeccah, Fallavollita JA, Canty J. Nonocclusive Multivessel Intracoronary Infusion of Allogeneic Cardiosphere-derived Cells Early After Reperfusion Prevents Remote Zone Myocyte Loss and Improves Global Left Ventricular Function in Swine with Myocardial Infarction. Am J Physiol Heart Circ Physiol. 2019; 317(2).

14. Weil BR, Techiryan, G, Suzuki G, Konecny, DVM, Canty J. Adaptive Reductions in Left Ventricular Diastolic Compliance Protect the Heart from Stretch-Induced Stunning. JACC: Basic to Translational Science. 2019; 4(4)

15. DAPA-HF Investigators. Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction New England Journal of Medicine. 2019; 381(21).

16. PARAGON-HF Investigators. Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction New England Journal of Medicine. 2019; 381(17).

17. Gordon JH, LaMonte MJ, Zhao J, Genco RJ, Cimato TR, Hovey KM, Allison MA, Mouton CP, Wactawski-Wende J. Association of Periodontal Disease and Edentulism With Hypertension Risk in Postmenopausal Women. Am J Hypertens. 2019; 32(2).

18. Cimato TR, Conway A, Nichols J, Wallace PK. CD133 expression in circulating hematopoietic progenitor cells. Cytometry B Clin Cytom. 2019; 96(1).

19. Knudsen ES, Pruitt SC, Hershberger PA, Witkiewicz AK, Goodrich DW. Cell Cycle and Beyond: Exploiting New RB1 Controlled Mechanisms for Cancer Therapy. Trends Cancer. 2019 May;5(5):308-324. doi: 10.1016/j.trecan.2019.03.005. Epub 2019 Apr 30. Review. PubMed PMID: 31174843; PubMed Central PMCID: PMC6719339

20. Carter KA, Luo D, Geng J, Stern ST, Lovell JF. Blood Interactions, Pharmacokinetics, and Depth-Dependent Ablation of Rat Mammary Tumors with Photoactivatable, Liposomal Doxorubicin. Mol Cancer Ther. 2019; 18(3).

21. Sun H, Yan L, Carter KA, Zhang J, Caserto JS, Lovell JF, Wu Y, Cheng C. Zwitterionic Cross-Linked Biodegradable Nanocapsules for Cancer Imaging. Langmuir. 2019; 35(5).

22. Dong X, Liu HJ, Feng HY, Yang SC, Liu XL, Lai X, Lu Q, Lovell JF, Chen HZ, Fang C. Enhanced Drug Delivery by Nanoscale Integration of a Nitric Oxide Donor To Induce Tumor Collagen Depletion. Nano Lett. 2019; 19(2).

23. Yang X, Lovell JF, Zhang Y. Ingestible Contrast Agents for Gastrointestinal Imaging. Chembiochem. 2019; 20(4).

24. Miranda D, Huang H, Kang H, Zhan Y, Wang D, Zhou Y, Geng J, Kilian HI, Stiles W, Razi A, Ortega J, Xia J, Choi HS, Lovell JF. Highly-Soluble Cyanine J-aggregates Entrapped by Liposomes for In Vivo Optical Imaging around 930 nm. Theranostics. 2019; 9(2).

25. Luo D, Carter KA, Molins EAG, Straubinger NL, Geng J, Shao S, Jusko WJ, Straubinger RM, Lovell JF. Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals. J Control Release. 2019; 297.

26. Shao S, Rajendiran V, Lovell JF. Metalloporphyrin Nanoparticles: Coordinating Diverse Theranostic Functions. Coord Chem Rev. 2019; 379

27. S. Neelamegham, K. Aoki-kinoshita, E. Bolton, M. Frank, F. Lisacek, T. Lutteke, N. O'boyle, N. H. Packer, P. Stanley, P. Toukach, A. Varki, R. J. Woods, A. Darvill, A. Dell, B. Henrissat, C. Bertozzi, G. Hart, H. Narimatsu, H. Freeze, I. Yamada, J. Paulson, J. Prestegard, J. Marth, J. F. G. Vliegenthart, M. Etzler, M. Aebi, M. Kanehisa, N. Taniguchi, N. Edwards, P. Rudd, P. Seeberger, R. Mazumder, R. Ranzinger, R. Cummings, R. Schnaar, S. Perez, S. Kornfeld, T. Kinoshita, W. York, Y. Knirel, “Updates to the Symbol Nomenclature for Glycans guidelines”, Glycobiology 29, 620-624 (2019).

28. E. E. Irons, M. M. Lee-sundlov, Y. Q. Zhu, S. Neelamegham, K. M. Hoffmeistee, J. T. Y. Lau, “B cells suppress medullary granulopoiesis by an extracellular glycosylation- dependent mechanism”, eLife 8, e47328 (2019).

29. M. Nasirikenari, A. A. Lugade, S. Neelamegham, Z. W. Gao, K. W. Moremen, P. N. Bogner, Y. Thanavala, J. T. Y. Lau, “Recombinant Sialyltransferase Infusion Mitigates Infection-Driven Acute Lung Inflammation”, Front. Immunol. 10, 48 (2019).

30. C. J. Zhang, A. Kelkar, S. Neelamegham, “von Willebrand factor self-association is regulated by the shear-dependent unfolding of the A2 domain”, Blood Adv. 3, 957-968 (2019).

31. Z. W. Chen, J. K. Lu, C. J. Zhang, I. Hsia, X. H. Yu, L. Marecki, E. Marecki, M. Asmani, S. Jain, S. Neelamegham, R. G. Zhao, “Microclot array elastometry for integrated measurement of thrombus formation and clot biomechanics under fluid shear”, Nat. Commun. 10, 2051 (2019).

32. B. R. Weil, S. Neelamegham, “Selectins and Immune Cells in Acute Myocardial Infarction and Post-infarction Ventricular Remodeling: Pathophysiology and Novel Treatments”, Front. Immunol. 10, 300 (2019).

33. Twum DY, Colligan SH, Hoffend NC, Katsuta E, Cortes Gomez E, Hensen ML, Seshadri M, Nemeth MJ, Abrams SI. IFN regulatory factor-8 expression in macrophages governs an antimetastatic program. JCI Insight. 2019 Feb 7;4(3). doi: 10.1172/jci.insight.124267 PubMed PMID: 30728331; PubMed Central PMCID: PMC6413790.

34. F. Y. Zhou, A. Kroetsch, V. P. Nguyen, X. Huang, O. Ogoke, N. Parashurama, S. Park, “High-Affinity Antibody Detection with a Bivalent Circularized Peptide Containing Antibody-Binding Domains”, Biotechnol. J. 14, 1800647 (2019)

Publications 2018

1. Harris, L., O. Zalucki, O. Clement, J. Fraser, E. Matuzelski, S. Oishi, T. J. Harvey, T. H. J. Burne, J. I. Heng, R. M. Gronostajski, and M. Piper. Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expressionDevelopment 145 (2018) PMID:29437824 

2. Oishi, S., D. Harkins, N. D. Kurniawan, M. Kasherman, L. Harris, O. Zalucki, R. M. Gronostajski, T. H. J. Burne, and M. Piper. Heterozygosity for Nuclear Factor One X in mice models features of Malan syndromeEBioMedicine (2018) PMID:30503862 

3. Schanze, I., J. Bunt, J. W. C. Lim, D. Schanze, R. J. Dean, M. Alders, P. Blanchet, T. Attie-Bitach, S. Berland, S. Boogert, S. Boppudi, C. J. Bridges, M. T. Cho, W. B. Dobyns, D. Donnai, J. Douglas, D. L. Earl, T. J. Edwards, L. Faivre, B. Fregeau, D. Genevieve, M. Gerard, V. Gatinois, M. Holder-Espinasse, S. F. Huth, K. Izumi, B. Kerr, E. Lacaze, P. Lakeman, S. Mahida, G. M. Mirzaa, S. M. Morgan, C. Nowak, H. Peeters, F. Petit, D. T. Pilz, J. Puechberty, E. Reinstein, J. B. Riviere, A. B. Santani, A. Schneider, E. H. Sherr, C. Smith-Hicks, I. Wieland, E. Zackai, X. Zhao, R. M. Gronostajski, M. Zenker, and L. J. Richards. NFIB Haploinsufficiency Is Associated with Intellectual Disability and MacrocephalyAm. J. Hum. Genet. 103 (2018) 752-68. PMID:30388402 

4. Vidovic, D., R. A. Davila, R. M. Gronostajski, T. J. Harvey, and M. Piper. Transcriptional regulation of ependymal cell maturation within the postnatal brainNeural Dev 13 (2018) 2. PMID:29452604 

5. Zalucki, O., D. Harkins, L. Harris, T. H. J. Burne, R. M. Gronostajski, and M. Piper. Analysis of hippocampal-dependent learning and memory behaviour in mice lacking Nfix from adult neural stem cellsBMC Res Notes 11 (2018) 564. PMID:30081965 PMC:PMC6080370

6. Zalucki, O., L. Harris, T. J. Harvey, D. Harkins, J. Widagdo, S. Oishi, E. Matuzelski, X. L. H. Yong, H. Schmidt, V. Anggono, T. H. J. Burne, R. M. Gronostajski, and M. Piper. NFIX-Mediated Inhibition of Neuroblast Branching Regulates Migration Within the Adult Mouse Ventricular-Subventricular ZoneCereb. Cortex (2018) PMID:30272140 

7. A. Shahini, K. Vydiam, D. Choudhury, N. Rajabian, T. Nguyen, P. Lei, S. T. Andreadis, “Efficient and high yield isolation of myoblasts from skeletal muscle”, Stem Cell Res. 30, 122-129 (2018).

8. G. Tseropoulos, S. M. Boroujeni, V. K. Bajpai, P. Lei, S. T. Andreadis, “Derivation of neural crest stem cells from human epidermal keratinocytes requires FGF-2, IGF-1, and inhibition of TGF-beta 1”, Bioeng. Transl. Med. 3, 256-264 (2018).

9. A. Shahini, D. Choudhury, M. Asmani, R. G. Zhao, P. Lei, S. T. Andreadis, “NANOG restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings”, Stem Cell Res. 26, 55-66 (2018).

10. Wang, J, Seo, M, Deci, MB, Weil BR, Canty J, Nguyen J. The role of heart rate variability, heart rate turbulence, and deceleration capacity in predicting cause-specific mortality in chronic heart failure.. Int J Nanomedicine. 2018; 13.

11. Wang J, Seo MJ, Deci MB, Weil BR, Canty JM, Nguyen J. Effect of CCR2 inhibitor-loaded lipid micelles on inflammatory cell migration and cardiac function after myocardial infarction.. Int J Nanomedicine. 2018; 13.

12. Techiryan G, Weil BR, Palka BA, Canty JM. Effect of Intracoronary Metformin on Myocardial Infarct Size in Swine.. Circ Res. 2018; 123(8).

13. Weil BR, Suzuki G, Young, R, Iyer VS, Canty J. Cardiac Troponin I Release and Reversible Left Ventricular Dysfunction Following Transient Pressure Overload: Stretch-Induced Myocardial Stunning. J Am Coll Cardiology. 2018; 71(25).

14. Zhang, M, An, B, Qu, Y, Shen, S, Fu, W, Chen, Y, Wang, X, Young, R, Canty J, Balthasar, J, Murphy, K, Bhattacharyya, D, Josephs, J, Ferrari, L, Zhou, S, Bansal, S, Vazvaie, F, Qu, J. A sensitive, high-throughput and robust Trapping Micro-LC-MS strategy for Quantification of Biomarkers and Antibody Biotherapeutics.. Anal Chem.. 2018; 90(3).

15. Ferguson SW, Wang, J, Lee, CJ, Liu, M, Neelamegham S, Canty J, Nguyen, J.. The microRNA regulatory landscape of mesenchymal stem cell-derived exosomes: a systems view.. Sci Rep.. 2018; 8(1).

16. Lindsey, ML, Boli, R, Canty J, Du, S-J, Frangogiannis, NG, Frantz, S, Gourdie, RG, Homes, JW, Jones, SP, Kloner, RA, Lefer, D, Liao, R, Murphy, E, Ping, P, Przyklenk, K, Recchia, FA, Schwartz-Longacre L, Ripplinger, CM, Van Eyk, JE, Heusch, G, None. Guidelines for Experimental Models of Myocardial Ischemia and Infarction.. Am J. Physiol. Heart and Circulatory. 2018; 214(4).

17. Gordon JH, LaMonte MJ, Genco RJ, Zhao J, Cimato TR, Hovey KM, Wactawski-Wende J. Association of clinical measures of periodontal disease with blood pressure and hypertension among postmenopausal women. J Periodontol. 2018

18. Gordon JH, LaMonte MJ, Genco RJ, Zhao J, Cimato TR, Hovey KM, Wactawski-Wende J. Association of clinical measures of periodontal disease with blood pressure and hypertension among postmenopausal women. J Periodontol. 2018.

19. Huang WC, Deng B, Lin C, Carter KA, Geng J, Razi A, He X, Chitgupi U, Federizon J, Sun B, Long CA, Ortega J, Dutta S, King CR, Miura K, Lee SM, Lovell JF. A malaria vaccine adjuvant based on recombinant antigen binding to liposomes. Nat Nanotechnol. 2018; 13(12)

20. S. Chugh, S. Barkeer, S. Rachagani, R. K. Nimmakayala, N. Perumal, R. Pothuraju, P. Atri, S. Mahapatra, I. Thapa, G. A. Talmon, L. M. Smith, X. H. Yu, S. Neelamegham, J. X. Fu, L. J. Xia, M. P. Ponnusamy, S. K. Batra, “Disruption of C1galt1 Gene Promotes Development and Metastasis of Pancreatic Adenocarcinomas in Mice”, Gastroenterology 155, 1608-1624 (2018)

21. S. S. Wang, X. F. Gao, V. del solar, X. H. Yu, A. Antonopoulos, A. E. Friedman, E. K. Matich, G. E. Atilla-gokcumen, M. Nasirikenari, J. T. Lau, A. Dell, S. M. Haslam, R. A. Laine, K. L. Matta, S. Neelamegham, “Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion”, Cell Chem. Biol. 25, 1519-+ (2018)

22. C. Zhang, A. Kelkar, M. Nasirikenari, T. Y. Lau, M. Sveinsson, U. C. Sharma, S. Pokharel, S. Neelamegham, “The physical spacing between the von Willebrand factor D'D3 and A1 domains regulates platelet adhesion in vitro and in vivo”, J. Thromb. Haemost. 16, 571-582 (2018)

23. S. W. Ferguson, J. L. Wang, C. J. Lee, M. X. Liu, S. Neelamegham, J. M. Canty, J. Nguyen, “The microRNA regulatory landscape of MSC-derived exosomes: a systems view”, Sci Rep 8, 1419 (2018)

24. M. Willadsen, M. Chaise, I. Yarovoy, A. Q. Zhang, N. Parashurama, “Engineering molecular imaging strategies for regenerative medicine”, Bioeng. Transl. Med. 3, 232-255 (2018).

25. K. E. Denson, A. L. Mussell, H. Shen, A. Truskinovsky, N. Yang, N. Parashurama, Y. M. Chen, C. Frangou, F. J. Yang, J. M. Zhang, “The Hippo Signaling Transducer TAZ Regulates Mammary Gland Morphogenesis and Carcinogen-induced Mammary Tumorigenesis”, Sci Rep 8, 6449 (2018)

26. Wang J, Saraswat D, Sinha AK, Polanco J, Dietz K, O'Bara MA, Pol SU, Shayya HJ, Sim FJ. Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors. Cell Rep. 2018; 25(12).

27. Welliver RR, Polanco JJ, Seidman RA, Sinha AK, O‘Bara MA, Khaku ZM, Santiago González DA, Nishiyama A, Wess J, Feltri ML, Paez PM, Sim FJ. Muscarinic receptor M3R signaling prevents efficient remyelination by human and mouse oligodendrocyte progenitor cells. J Neurosci. 2018.

28. Kumar S, Wilkes DW, Samuel N, Blanco MA, Nayak A, Alicea-Torres K, Gluck C, Sinha S, Gabrilovich D, Chakrabarti R. Î”Np63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer. J Clin Invest. 2018; 128(11).

29. Fan X, Wang D, Burgmaier JE, Teng Y, Romano R, Sinha S, Yi R. Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin. Dev Cell. 2018; 47(1).

30. Russo C, Osterburg C, Sirico A, Antonini D, Ambrosio R, Würz JM, Rinnenthal J, Ferniani M, Kehrloesser S, Schäfer B, Güntert P, Sinha S, Dötsch V, Missero C. Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome. Proc Natl Acad Sci U S A. 2018; 115(5)

Publications 2017

1. K. Nam, C. S. Wang, C. L. M. Maruyama, P. Lei, S. T. Andreadis, O. J. Baker, “L1 Peptide-Conjugated Fibrin Hydrogels Promote Salivary Gland Regeneration”, J. Dent. Res. 96, 798-806 (2017).

2. P. Mistriotis, S. T. Andreadis, “Vascular aging: Molecular mechanisms and potential treatments for vascular rejuvenation”, Ageing Res. Rev. 37, 94-116 (2017).

3. K. Nam, C. L. Maruyama, C. S. Wang, B. G. Trump, P. Lei, S. T. Andreadis, O. J. Baker, “Laminin-111-derived peptide conjugated fibrin hydrogel restores salivary gland function”, PLoS One 12, e0187069 (2017).

4. D. Verma, V. K. Bajpai, N. N. Ye, M. M. Maneshi, D. Jetta, S. T. Andreadis, F. Sachs, S. Z. Hua, “Flow induced adherens junction remodeling driven by cytoskeletal forces”, Exp. Cell Res. 359, 327-336 (2017).

5. A. Shahini, P. Mistriotis, M. Asmani, R. G. Zhao, S. T. Andreadis, “NANOG Restores Contractility of Mesenchymal Stem Cell-Based Senescent Microtissues”, Tissue Eng. Part A 23, 535-+ (2017).

6. V. K. Bajpai, L. Kerosuo, G. Tseropoulos, K. A. Cummings, X. Y. Wang, P. Lei, B. Liu, S. Liu, G. K. Popescu, M. E. Bronner, S. T. Andreadis, “Reprogramming Postnatal Human Epidermal Keratinocytes Toward Functional Neural Crest Fates”, Stem Cells 35, 1402-1415 (2017). PDF

7. S. Row, A. Santandreu, D. D. Swartz, S. T. Andreadis, “Cell-free vascular grafts: Recent developments and clinical potential”, Technology 5, 13-20 (2017).

8. P. Mistriotis, V. K. Bajpai, X. Y. Wang, N. Rong, A. Shahini, M. Asmani, M. S. Liang, J. M. Wang, P. Lei, S. Liu, R. G. Zhao, S. T. Andreadis, “NANOG Reverses the Myogenic Differentiation Potential of Senescent Stem Cells by Restoring ACTIN Filamentous Organization and SRF-Dependent Gene Expression”, Stem Cells 35, 207-221 (2017).

9. Fallavollita JA, Dare, JD, Carter, RL, Baldwa S, Canty J. Denervated myocardium preferentially predicts sudden cardiac arrest in ischemic cardiomyopathy: A competing risk analysis of cause-specific mortality. Circulation: Cardiovascular Imaging. 2017; 10(8).

10. Weil BR, Young, Rebeccah, Shen, Xiaomeng, Suzuki G, Qu J, Malhotra S, Canty J. Brief Myocardial Ischemia Produces Cardiac Troponin I Release and Focal Myocyte Apoptosis in the Absence of Pathological Infarction in Swine.. J Am Coll Cardiol Basic Trans Science. 2017; 2(2).

11. Malhotra, S and Canty, Jr. JM. Vasodilator stress and left ventricular asynchrony. Journal of Nuclear Cardiology. 2017; 24(1).

12. Fallavollita JA, JD Dare, RL Carter, S Baldwa and JM Canty Jr.. Denervated myocardium is preferentially associated with sudden cardiac arrest in ischemic cardiomyopathy. A pilot competing risks analysis of cause-specific mortality.. Circ Cardiovascular Imaging. 2017; 10.

13. Weil BR, RF Young, X Shen, G Suzuki, JK Qu, S Malhotra and JM Canty, Jr.. Brief myocardial ischemia produces cardiac troponin I release and focal myocyte apoptosis in the absence of pathological infarction in swine. J Am Coll Cardiol Basic Trans Sci. 2017; 2(2).

14. Canty, Jr. JM and BR Weil.. Cortical Bone Stem Cells Administered at Reperfusion Attenuate Adverse Post-Infarction Left Ventricular Remodeling and Prevent Myocyte Loss at a Distance.. Circulation Research. 2017; 121.

15. Canty, Jr. JM. Is it still important to evaluate patients with ischemic cardiomyopathy for viable dysfunctional myocardium prior to myocardial revascularization?. Trends in Cardiovascular Medicine. 2017; 17.

16. Malhorta S and Canty, Jr. JM. American Perspective: Comparing the AHA/ACC and ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death.. Journal of Nuclear Cardiology. 2017.

17. Sharma UC, W Mosleh, MR Chaudhari, R Katkar, B Weil, C Evelo, TR Cimato, S Pokharel, WM Blenkesteijn, G Suzuki.. Myocardial and serum galectin-3 expression dynamics marks post-myocardial infarction cardiac remodeling.. Heart Lung Circulation. 2017; 26(7).

18. Cimato TR. Biological Age and Circulating Progenitor Cell Levels as Predictors Heart Disease Events. Circulation Research. 2017; 120(7).

19. Sharma UC, W Mosleh, MR Chaudhari, R Katkar, B Weil, C Evelo, TR Cimato, S Pokharel, WM Blenkesteijn, G Suzuki.. Myocardial and serum galectin-3 expression dynamics marks post-myocardial infarction cardiac remodeling.. Heart Lung Circulation. 2017; 26(7).

20. Cimato TR. Biological Age and Circulating Progenitor Cell Levels as Predictors Heart Disease Events. Circulation Research. 2017; 120(7).

21. Matuzelski E, Bunt J, Harkins D, Lim JWC, Gronostajski RM, Richards LJ, Harris L, Piper M. Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Dev Biol. 2017; 432(2).

22. Becker-Santos DD, Lonergan KM, Gronostajski RM, Lam WL. Nuclear Factor I/B: A Master Regulator of Cell Differentiation with Paradoxical Roles in Cancer. EBioMedicine. 2017; 22.

23. Chen KS, Harris L, Lim JWC, Harvey TJ, Piper M, Gronostajski RM, Richards LJ, Bunt J. Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice. J Comp Neurol. 2017; 525(11).

24. Fraser J, Essebier A, Gronostajski RM, Boden M, Wainwright BJ, Harvey TJ, Piper M. Cell-type-specific expression of NFIX in the developing and adult cerebellum. Brain Struct Funct. 2017; 222(5).

25. A. Momeni, S. Neelamegham, N. Parashurama, “Current challenges for the targeted delivery and molecular imaging of stem cells in animal models”, Bioengineered 8, 316-324 (2017)

26. S. Gogia, A. Kelkar, C. J. Zhang, K. M. Dayananda, S. Neelamegham, “Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13”, Blood Adv. 1, 2063-2074 (2017)

27. C. J. Zhang, S. Neelamegham, “Application of microfluidic devices in studies of thrombosis and hemostasis”, Platelets 28, 434-440 (2017)

28. U. Chitgupi, Y. Li, M. F. Chen, S. Shao, M. Beitelshees, M. J. Tan, S. Neelamegham, B. A. Pfeifer, C. Jones, J. F. Lovell, “Bimodal Targeting Using Sulfonated, Mannosylated PEI for Combined Gene Delivery and Photodynamic Therapy”, Photochem. Photobiol. 93, 600-608 (2017).

29. K. Cheng, Y. S. Zhou, S. Neelamegham, “DrawGlycan-SNFG: a robust tool to render glycans and glycopeptides with fragmentation information”, Glycobiology 27, 200-205 (2017).

30. A. Buffone, M. Nasirikenari, C. T. Manhardt, A. Lugade, P. N. Bogner, R. Sackstein, Y. Thanavala, S. Neelamegham, J. T. Y. Lau, “Leukocyte-borne alpha(1,3)-fucose is a negative regulator of beta(2)-integrin-dependent recruitment in lung inflammation”, J. Leukoc. Biol. 101, 459-470 (2017)

31. Griffiths EA, Srivastava P, Matsuzaki J, Brumberger Z, Wang ES, Kocent J, Miller A, Roloff GW, Wong HY, Paluch BE, Lutgen-Dunckley LG, Martens BL, Odunsi K, Karpf AR, Hourigan CS, Nemeth MJ. NY- ESO-1 Vaccination in Combination with Decitabine Induces Antigen-Specific T-Lymphocyte Responses in Patients with Myelodysplastic Syndrome. Clin Cancer Res. 2018 Mar 1;24(5):1019-1029. doi: 10.1158/1078-0432.CCR-17-1792. Epub 2017 Sep 25. PMID: 28947565. PMCID: PMC5844797

32. A. Momeni, S. Neelamegham, N. Parashurama, “Current challenges for the targeted delivery and molecular imaging of stem cells in animal models”, Bioengineered 8, 316-324 (2017)

33. O. Ogoke, J. Oluwole, N. Parashurama, “Bioengineering considerations in liver regenerative medicine”, J. Biol. Eng. 11, 46 (2017)

34. Martin JA, Caccamise A, Werner CT, Viswanathan R, Polanco JJ, Stewart AF, Thomas SA, Sim FJ, Dietz DM. A Novel Role for Oligodendrocyte Precursor Cells (OPCs) and Sox10 in Mediating Cellular and Behavioral Responses to Heroin. Neuropsychopharmacology. 2017.

35. Pol SU, Polanco JJ, Seidman RA, O‘Bara MA, Shayya HJ, Dietz KC, Sim FJ. Network-Based Genomic Analysis of Human Oligodendrocyte Progenitor Differentiation. Stem Cell Reports. 2017; 9(2).

36. Wang ZJ, Martin JA, Gancarz AM, Adank DN, Sim FJ, Dietz DM. Activin A is increased in the nucleus accumbens following a cocaine binge. Sci Rep. 2017; 7

Publications 2016

1. S. Row, C. Koenigsknecht, M.T. Koobatian, A. Shahini, S.T. Andreadis, D.D. Swartz. (2016). Development of a Hypertensive Ovine model for the Evaluation of Autologous Vascular Grafts. Annals of Surgery: International 2(7): 1-16.

2.H. Lee, D. Koh, L. Xu, S. Row, S.T. Andreadis and Kwang W. Oh (2016). A simple method for fabrication of microstructures using PDMS stamp. Micromachines 7(10)173.

3. S. Row, Y. Liu, S. Alimperti, S.K. Agarwal and S.T. Andreadis (2016). Cadherin-11 is a Novel Regulator of Extracellular Matrix Synthesis and Tissue Mechanics. J. Cell Sci. 129(15): 2950-61

4. Y. Li, M. Beitelshees, L. Fang, A. Hill, M.K. Ahmadi, M. Chen, B. Davidson, P. Knight III, R.J. Smith Jr, S.T. Andreadis, A. Hakansson, C.H. Jones, B.A. Pfeifer (2016). In situ Pneumococcal Vaccine Production and Delivery through a Hybrid Biological-biomaterial Vector. Science Advances 2(7): e1600264; doi: 10.1126.

4. X. Yuan, R.J Smith Jr., H. Guan, C.N. Ionita, P. Khobragade, R. Dziak, Z. Liu, M. Pan, C. Wang, G. Guan, S.T. Andreadis, S. Yang (2016). Hybrid Biomaterial with Conjugated Growth factors and Mesenchymal Stem Cells for Ectopic Bone Formation. Tissue Eng. (Part A) 22(13-14): 928-39.

5. K. Nam, P. Lei, S.T. Andreadis and O.J. Baker (2016). Laminin-111 Peptides Conjugated to Fibrin Hydrogels Promote Formation of Lumen Containing Parotid Gland Cell Clusters. Biomacromolecules 17(6): 2293-301.

6. M. T. Koobatian, S. Row, R. Smith, C. Koenigsknecht, S.T. Andreadis*, D.D. Swartz* (2016). Development of an Acellular Off the Shelf Small Diameter Blood Vessel Evaluated In a Large Animal Model. Biomaterials 76: 344-358 (* co-corresponding author)

7. Weil BR, Konecny F, Suzuki G, Iyer V, Canty JM. Comparative Hemodynamic Effects of Contemporary Percutaneous Mechanical Circulatory Support Devices in a Porcine Model of Acute Myocardial Infarction.. JACC Cardiovasc Interv. 2016; 9(22).

8. Canty J, Weil BR, Suzuki G. Widespread Intracoronary Cardiopoietic Cell Infusion: Treating at the Time of Myocardial Reperfusion to Prevent Rather Than Reverse Established Left Ventricular Dysfunction Moves Us Closer to Practical Clinical Translation. Circ Res. 2016; 118(7).

9. Zlotnick DM and Canty JM Jr. Striking a balance: Individualizing antithrombotic therapy after myocardial infarction. Trends in Cardiovascular Medicine. 2016; 74.

10. Canty J, Weil BR, Suzuki G. Widespread Intracoronary Cardiopoietic Cell Infusion - treating at the Time of Myocardial Reperfusion to Prevent Rather than Reverse Established Left Ventricular Dysfunction Moves us closer to Practical Clinical Translation.. Circ Res.. 2016; 118.

11. Malhotra S, Canty JM. Life-Threatening Ventricular Arrhythmias: Current Role of Imaging in Diagnosis and Risk Assessment.. J Nucl Cardiol. 2016.

12. Lo CY, Weil BR, Palka BA, Momeni A, Canty JM Jr. and Neelamegham S. Cell Surface Glycoengineering Improves Selectin-mediated Adhesion of Mesenchymal Stem Cells (MSCs) and Cardiosphere-derived Cells (CDCs); Pilot Validation in Porcine Ischemia-Reperfusion Model. Biomaterials. 2016; 74

13. Harris L, Zalucki O, Gobius I, McDonald H, Osinki J, Harvey TJ, Essebier A, Vidovic D, Gladwyn-Ng I, Burne TH, Heng JI, Richards LJ, Gronostajski RM, Piper M. Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development. 2016; 143(24).

14. Wu N, Jia D, Ibrahim AH, Bachurski CJ, Gronostajski RM, MacPherson D. NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer. Oncotarget. 2016; 7(36).

15. Ding B, Cave JW, Dobner PR, Mullikin-Kilpatrick D, Bartzokis M, Zhu H, Chow CW, Gronostajski RM, Kilpatrick DL. Reciprocal autoregulation by NFI occupancy and ETV1 promotes the developmental expression of dendrite-synapse genes in cerebellar granule neurons. Mol Biol Cell. 2016; 27(9).

16. Grabowska MM, Kelly SM, Reese AL, Cates JM, Case TC, Zhang J, DeGraff DJ, Strand DW, Miller NL, Clark PE, Hayward SW, Gronostajski RM, Anderson PD, Matusik RJ. Nfib Regulates Transcriptional Networks That Control the Development of Prostatic Hyperplasia. Endocrinology. 2016; 157(3).

17. Zhang Y, Song W, Geng J, Chitgupi U, Unsal H, Federizon J, Rzayev J, Sukumaran DK, Alexandridis P, Lovell JF. Therapeutic surfactant-stripped frozen micelles. Nat Commun. 2016; 7

18. S. Neelamegham, L. K. Mahal, “Multi-level regulation of cellular glycosylation: from genes to transcript to enzyme to structure”, Curr. Opin. Struct. Biol. 40, 145-152 (2016).

19.E. V. Chandrasekaran, J. Xue, J. Xia, S. D. Khaja, C. F. Piskorz, R. D. Locke, S. Neelamegham, K. L. Matta, “Novel interactions of complex carbohydrates with peanut (PNA), Ricinus communis (RCA-I), Sambucus nigra (SNA-I) and wheat germ (WGA) agglutinins as revealed by the binding specificities of these lectins towards mucin core-2 O-linked and N-linked glycans and related structures”, Glycoconjugate J. 33, 819-836 (2016).

20. G. Stolfa, N. Mondal, Y. Q. Zhu, X. H. Yu, A. Buffone, S. Neelamegham, “Using CRISPR-Cas9 to quantify the contributions of O-glycans, N-glycans and Glycosphingolipids to human leukocyte-endothelium adhesion”, Sci Rep 6, 30392 (2016).

21. A. Nascimbene, S. Neelamegham, O. H. Frazier, J. L. Moake, J. F. Dong, “Acquired von Willebrand syndrome associated with left ventricular assist device”, Blood 127, 3133-3141 (2016).

22. N. Mondal, G. Stolfa, A. Antonopoulos, Y. Q. Zhu, S. S. Wang, A. Buffone, G. E. Atilla-gokcumen, S. M. Haslam, A. Dell, S. Neelamegham, “Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin-Dependent Rolling in the Multistep Leukocyte Adhesion Cascade”, Arterioscler. Thromb. Vasc. Biol. 36, 718-727 (2016).

23. S. Gogia, S. Neelamegham, “Role of fluid shear stress in regulating VWF structure, function and related blood disorders”, Biorheology 52, 319-335 (2016).

24. R. Gupta, K. L. Matta, S. Neelamegham, “A systematic analysis of acceptor specificity and reaction kinetics of five human alpha(2,3)sialyltransferases: Product inhibition studies illustrate reaction mechanism for ST3Gal-I”, Biochem. Biophys. Res. Commun. 469, 606-612 (2016).

25. C. Y. Lo, B. R. Weil, B. A. Palka, A. Momeni, J. M. Canty, S. Neelamegham, “Cell surface glycoengineering improves selectin-mediated adhesion of mesenchymal stem cells (MSCs) and cardiosphere-derived cells (CDCs): Pilot validation in porcine ischemia-reperfusion model”, Biomaterials 74, 19-30 (2016)

26. Srivastava P, Paluch BE, Matsuzaki J, James SR, Collamat-Lai G, Blagitko-Dorfs N, Ford LA, Naqash R, Lübbert M, Karpf AR, Nemeth MJ (Co-Senior Author), Griffiths EA. Induction of cancer testis antigen expression in circulating acute myeloid leukemia blasts following hypomethylating agent monotherapy. Oncotarget. 2016 Mar 15;7(11):12840-56. doi: 10.18632/oncotarget.7326 Epub 2016 Feb 11. PMID: 26883197. PMCID: PMC4914325

27. Paluch BE, Naqash AR, Brumberger Z, Nemeth MJ, Griffiths EA. Epigenetics: A primer for clinicians. Blood Rev. 2016 Jul;30(4):285-95. doi: 10.1016/j.blre.2016.02.002. Epub 2016 Feb 26. Review. PubMed PMID: 26969414; PubMed Central PMCID: PMC5737767

28. Komorowski MP, McGray AR, Kolakowska A, Eng K, Gil M, Opyrchal M, Litwinska B, Nemeth MJ, Odunsi KO, Kozbor D. Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy. Mol Ther Oncolytics. 2016;3:16034. doi: 10.1038/mto.2016.34. eCollection 2016. PubMed PMID: 28035333; PubMed Central PMCID: PMC5155641

29. N. Parashurama, B. C. Ahn, K. Ziv, K. Ito, R. Paulmurugan, J. K. Willmann, J. Chung, F. Ikeno, J. C. Swanson, D. R. Merk, J. K. Lyons, D. Yerushalmi, T. Teramoto, H. Kosuge, C. N. Dao, P. Ray, M. Patel, Y. F. Chang, M. Mahmoudi, J. E. Cohen, A. B. Goldstone, F. Habte, S. Bhaumik, S. Yaghoubi, R. C. Robbins, R. Dash, P. C. Yang, T. J. Brinton, P. G. Yock, M. V. Mcconnell, S. S. Gambhir, “Multimodality Molecular Imaging of Cardiac Cell Transplantation: Part II. In Vivo Imaging of Bone Marrow Stromal Cells in Swine with PET/CT and MR Imaging”, Radiology 280, 826-836 (2016).

30. N. Parashurama, B. C. Ahn, K. Ziv, K. Ito, R. Paulmurugan, J. K. Willmann, J. Chung, F. Ikeno, J. C. Swanson, D. R. Merk, J. K. Lyons, D. Yerushalmi, T. Teramoto, H. Kosuge, C. N. Dao, P. Ray, M. Patel, Y. F. Chang, M. Mahmoudi, J. E. Cohen, A. B. Goldstone, F. Habte, S. Bhaumik, S. Yaghoubi, R. C. Robbins, R. Dash, P. C. Yang, T. J. Brinton, P. G. Yock, M. V. Mcconnell, S. S. Gambhir, “Multimodality Molecular Imaging of Cardiac Cell Transplantation: Part I. Reporter Gene Design, Characterization, and Optical in Vivo Imaging of Bone Marrow Stromal Cells after Myocardial Infarction”, Radiology 280, 815-825 (2016)

31. Poitelon Y, Lopez-Anido C, Catignas K, Berti C, Palmisano M, Williamson C, Ameroso D, Abiko K, Hwang Y, Gregorieff A, Wrana JL, Asmani M, Zhao R, Sim FJ, Wrabetz L, Svaren J, Feltri ML.. YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells.. Nat Neurosci. 2016; 19(7).

32. Dietz KC, Polanco JJ, Pol SU, Sim FJ. Targeting human oligodendrocyte progenitors for myelin repair. Exp Neurol. 2016