Protocol Information

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Title The effect of rehydration and cooling strategies on biomarkers of kidney function
Description Rehydration, cooling, and renal function

Participant will be asked to complete research study within 21 hours, spread out over 5 study visits.

Study visits will be at the University at Buffalo, South Campus

If you're interested in this study, please contact the study coordinator listed below.
Objective An epidemic of chronic kidney disease is occurring in manual laborers who regularly work in hot environments. The reason is unclear, but it is likely that reductions in body water and increases in body temperature elicit acute kidney injury that, when repeated, leads to chronic kidney disease. In humans, physical work in the heat elicits acute and moderate increases in biomarkers of renal dysfunction. However, it is unknown if the previously observed changes in renal function are exacerbated when rehydrating during or after physical work in the heat, and if body cooling during these rehydration strategies attenuates the changes in renal function.

Keywords: Exercise, kidney function, healthy volunteer
Principal Investigator SCHLADER, ZACHARY
Age Group Adult
Drugs Involved
Status Open
Key Eligibility Ages 18-40
Self-reported to be healthy
Disease Group Healthy Volunteers