NewsCenter

UB Expert

Paresh Dandona

Expertise:

• Endocrinology, particularly as it relates to diabetes, thyroid abnormalities and heart disease
• The role of insulin and estrogen as anti-inflammatory agents that may help prevent the damage to blood vessel walls implicated in heart disease and on an influx of glucose and other macronutrients as promoters of inflammation
• The impact of oxygen free radicals on the inflammatory process as it relates to vessel disease
• His lab reported the first US cases of severe muscle weakness due to Vitamin D deficiency, and found severe deficiency of the vitamin in a cohort of Kashmiri women related to wearing of heavy clothing and the burkah
• His lab has shown that the insulin sensitizer Avandia also acts an an anti-inflammatory
• Earlier studies reported corticosteroids may slow generation of free radicals; free-radical production and damage increase with age; endothelial cells produce estrogen and estrogen receptor, and free radicals cause DNA damage to sperm of diabetic men

Dandona heads the Diabetes-Endocrinology Center of Western New York, which produces prolific research. Excellent ability to describe medical research in lay terms. Is good with the press and interested indiscussing his research.