Statistical Workshop Series

Phase- I Oncology Trials

Michael Sill.

Michael Sill, PhD

Senior Biostatistician

Department of Biostatistics and Bioinformatics,

Roswell Park Comprehensive Cancer Center

Research Associate Professor

Department of Biostatistics

University at Buffalo

Tuesday, February 25, 2020

4:00 – 6:00 PM

150 Farber Hall

South Campus

University at Buffalo

This workshop will introduce the primary goal of phase 1 designs for the treatment of cancer, which often is the search for the maximally tolerated dose (MTD). We will cover some basic concepts to better understand why we use the MTD, then cover the classic 3+3 design and discuss some of its drawbacks.

After a brief introduction to Bayesian statistics, we will finally cover some more sophisticated designs such as accelerated titration designs and model based, continual reassessment methods (CRM).

This workshop is free and open to all students, fellows, faculty and staff at UB and the Buffalo Translational Consortium.

REGISTER FOR THIS WORKSHOP BY FEB. 24

ACCREDITATION: The University at Buffalo Jacobs School of Medicine and Biomedical Sciences is accredited by the ACCME to provide continuing medical education for physicians.

CERTIFICATION: The University at Buffalo Jacobs School of Medicine and Biomedical Sciences designates this live activity for a maximum of 2.0 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CREDIT: This program is supported by the National Center for Advancing Translational Sciences of the National Institutes of Health under award number UL1TR001412.