Translational Pilot Studies Current and Past Awards

The pilot studies review process consists of an initial letter of intent which determines invitations for full RFPs (Requests For Proposals). The invited full proposals are then reviewed according to RFP criteria by faculty in a partner Clinical and Translational Science Award (CTSA) hub. 

Research implementation and participation

An operational principle for the UB Clinical and Translational Science Institute is to maximize the impact of our initiatives through a catalytic approach to the development and testing of new approaches to solving translational research problems, and to implementation and disseminatation of those approaches that work.

We conduct a robust pilot studies program to identify new methods for translation with an emphasis on strategies to better engage underserved populations. The program is designed to reward interdisciplinary collaboration by making it a review criterion.

We use CTSA and institutional funding to enhance innovation in engaging special populations -- including children, the elderly and those experiencing health disparities (all underrepresented in clinical studies) -- in clinical research projects.

Pilot Study Awards

2017-18 Pilot Study Awards

NEUTROPHIL-BASED BIOMARKERS IN JUVENILE IDIOPATHIC ARTHRITIS

James N. Jarvis, MD
Tao Liu, PhD

Jacobs School of Medicine and Biomedical Sciences

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BLOOD PRESSURE CONTROL IN CONCUSSION

Blair D. Johnson, MD 
John J. Leddy, MD 
Barry Willer, PhD 
Robert Zivadinov, MD, PhD 
Michael G. Dwyer, PhD 
Jeffrey C. Miecznikowski, PhD

School of Public Health and Health Professions 
Jacobs School of Medicine and Biomedical Sciences
School of Public Health and Health Professions

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CUTTING THE RISK OF COLORECTAL CANCER BY DEVELOPING A NOVEL, EVIDENCE-BASED, COMMUNITY-BASED PROGRAM FOR INCREASING SCREENING UPTAKE IN BLACK MALES

Jeffrey M. Lackner, PsyD
Kenyani Davis, MD, MPH
Brian M. Quigley, PhD
Joseph E. Ravenell, MD, MS

Jacobs School of Medicine and Biomedical Sciences
Research Institute on Addictions

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A RANDOMIZED CONTROLLED TRIAL OF EXERCISE TREATMENT FOR CONCUSSION

John Leddy, MD
Barry Willer, PhD
Jeffrey Miecznikowski, PhD
Scott Darling, MD

Jacobs School of Medicine and Biomedical Sciences
School of Public Health and Health Professions

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ROLE OF CONTINGENCY MANAGEMENT IN THE TREATMENT OF YOUTH AND THEIR PARENTS IN A PEDIATRIC TERTIARY CARE WEIGHT MANAGEMENT PROGRAM

Indrajit Majumdar, MBBS
Lucy Mastrandrea, MD, PhD
Andrew H. Talal, MD, MPH
Teresa Quattrin, MD
Carroll M. Harmon, MD, PhD
Leonard H. Epstein, PhD

Jacobs School of Medicine and Biomedical Sciences

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DETERMINANTS OF TREATMENT FAILURE IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) EXACERBATION

Manoj Jacob Mammen, MD, MS
Sanjay Sethi, MD 
Heather Ochs-Balcom, PhD 

Jacobs School of Medicine and Biomedical Sciences
School of Public Health and Health Professions

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THE DIAGNOSIS OF ANEURYSMAL SUBARACHNOID HEMORRHAGE (DaSH) STUDY

Robert F. McCormack, MD, MBA
Christine Verni, EdD 
Heather A. Lindstrom, PhD 

Jacobs School of Medicine and Biomedical Sciences
School of Public Health and Health Professions

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DISCOVERY OF CIRCADIAN MODULATORS SELECTIVELY TARGETING MELATONIN RECEPTORS

Rajendram V. Rajnarayanan, PhD 
Margarita L. Dubocovich, PhD 

Jacobs School of Medicine and Biomedical Sciences

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EXOSOMAL BIOMARKERS AS PREDICTORS OF SARCOPENIA AND FRAILTY IN WHI PARTICIPANTS

Jessica L. Reynolds, PhD
Bruce R. Troen, MD 
Jean Wactawski-Wende, PhD 

Jacobs School of Medicine and Biomedical Sciences
School of Public Health and Health Professions

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MULTIMODAL MULTIPARAMETRIC BRAIN MAPPING FOR PRE-SYMPTOMATIC DIAGNOSIS AND TREATMENT DEVELOPMENT IN KRABBE DISEASE

Ferdinand Schweser, PhD
Lawrence Wrabetz, MD
Sarah F. Muldoon, PhD
Robert Zivadinov, MD 

Jacobs School of Medicine and Biomedical Sciences
College of Arts and Sciences

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INTEGRATING NALTREXONE TREATMENT, ALCOHOLICS ANONYMOUS FACILITATION, AND THE OPRM1 POLYMORPHISM IN THE TREATMENT OF ALCOHOL DEPENDENT OUTPATIENTS

Kimberly S. Walitzer, PhD
Javier G. Blanco
Scott Stewart, MD
Denise Swiatek, PharmD 

Research Institute on Addictions
Jacobs School of Medicine and Biomedical Sciences
School of Pharmacy and Pharmaceutical Sciences

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THREE-DIMENSIONAL PHOTOACOUSTIC COMPUTED TOMOGRAPHY FOR DIAGNOSIS AND TREATMENT MONITORING OF CHRONIC LEG ULCERS

Jun Xia, PhD
Linda M. Harris, MD 

Jacobs School of Medicine and Biomedical Sciences

Past Awards: