A technician prepares a scan using UB's GE discovery PET-CT scanner, one of three high-powered scanners in the CTSI dedicated solely to research.
The following steps outline the general work flow for
investigators using the services of the Center for Biomedical
1. Consultation and Study Design
Request consultation: Initiate a request using the
CTSI service request portal.
Discuss logistics with CBI staff: experimental protocols,
number of subjects per group and time points, housing, injection
techniques, imaging techniques, resolution, tissue collection,
contrast agents, image reconstruction, image analyses and
PIs must have an approved IACUC/IRB protocol which includes the
CBI staff may provide assistance with the imaging-related
aspects of the regulatory approval.
3. Preclinical Protocols and Housing
External investigators must transfer preclinical models to the
CBI IACUC Protocol using the appropriate UB LAF procedure prior to
Models will need to be transported to the CTSI LAF facility
using the institutional transfer mechanisms and applicable
4. Clinical MRI and PET/CT studies
PIs must amend their protocol to include imaging procedures,
and have an approved IRB protocol. CBI staff may assist with the
IRB protocol creation.
Detailed guidelines for scheduling measurement time will be
provided after the initial consultation.
6. Imaging/Data Acquisition
CBI staff will take care of all aspects related to the imaging
7. Data Storage and Analysis
Depending on the investigator's needs, imaging data will be
converted to the required format and provided via an
internet-accessible data server.
CBI personnel may advise and provide training for image
analysis. Typically, image analysis is the investigator’s
responsibility or will be performed in collaboration with other UB
investigators, including those from Buffalo Neuroimaging Analysis
8. Manuscript and Publication Preparation
All published or otherwise presented work involving resources
of the CBI – including manuscripts, conference abstracts
and presentations – must must acknowledge the NIH CTSA
grant support as follows:
Research reported in this publication was funded by the National
Center for Advancing Translational Sciences of the National
Institutes of Health under award number UL1TR001412 to the
University at Buffalo. The content is solely the responsibility of
the authors and does not necessarily represent the official views
of the NIH.
Work that used the 3T Toshiba scanner must acknowledge the
Toshiba equipment grant as follows:
This study was supported by an equipment grant from Toshiba
Medical Systems Corporation and Toshiba Medical Research Institute,
CBI will provide assistance in the description of the employed
methods in publications. We may assist/provide guidance in
preparing images and videos.