Academia; Anti-Platelet Therapy and Anticoagulation; Blood-Brain Barrier and Brain Delivery; Clinical Research; HIV; Infectious Disease; Neuropharmacology; Pharmacogenomics; Pharmacokinetics; Toxicology
Dr. Ma has focused his research on pharmacotherapy of HIV-associated neurocognitive disorders. With a longer life expectancy, people living with long-term HIV infection exhibit clinical manifestations of aging early, such as multimorbidity, polypharmacy, and decline in cognitive abilities. Dr. Ma has developed a broad research program that has expanded and evolved into investigating pharmacokinetics and pharmacodynamics of antiretroviral therapy on the central nervous system, pharmacogenomics, drug-drug interactions, and polypharmacy in relation to neurocognitive function in the elderly living with HIV. His research projects involve a multidisciplinary team that encompasses pharmacy, clinical pharmacology, neurology, psychology, substance use disorders, and biomarker disciplines and utilize a variety of data and laboratory analytical techniques as well as cell culture and small animal models through collaborations.