Genomics

The Developmental Genomics group studies and analyzes gene expression patterns and genetic perturbations of model organisms to better understand the developmental processes of organisms and diseases.

The powerful combination of our nationally recognized UB faculty and staff, state-of-the-art equipment and high-performance computing resources is helping establish Buffalo Niagara as a national leader in genome research. Through this leadership, the CBLS will help usher in a new era of medicine.

The UB Genomics & Bioinformatics Core is the area’s first sequencing service provider and offers a wide range of genomic and epigenomic services on multiple platforms.

The core is located within the CBLS, and currently offers services on the following analysis platforms:

High-Throughput Sequencing

• illumina HiSeq2500
• Life Technologies' Ion PGM
• Life Technologies' Ion Proton

 Additional Genomic Technology Platforms and Services

• Affymetrix Genechip System
• Diagenode SX-8G Compact Automated Systems
• QX100 Droplet Digital PCR machine (Biorad)
• Agilent Microarray Scanner G2505C

Norma J. Nowak, PhD
Director of Science and Technology
New York State Center of Excellence in Bioinformatics & Life Sciences
716 881 8903
njnowak@buffalo.edu

Norma Jean Nowak, PhD, is recognized as a leader in the field of human genomics. Her research contributed directly to the Human Genome Project, as well as to microarray-based approaches to understanding heritable disorders and cancer. In addition to her leadership role at the CBLS, Dr. Nowak is the founder and chief scientific officer of Empire Genomics LLC, a molecular diagnostics firm focused on enabling personalized medicine.

Among her major achievements, Nowak has authored landmark papers describing the cloning of several heritable cancer disorders, and her work on the Human Genome Project was published in the genome issue of Nature. Dr. Nowak also led and coordinated the three groups for the National Cancer Institute’s extramural Cancer Chromosome Aberration Project, and was a key member of the GENSAT project. She has authored or co-authored more than 140 research articles in leading scientific journals, has served as an associate editor of Physiological Genomics, and is currently on the editorial board of Cytogenetic and Genome Research as an associate editor.

For more information about UB's Genomics & Bioinformatics Core, please contact:

Sujith Valiyaparambil
Research Associate
716 881 7514
alphy@buffalo.edu