Genomics

Dr. Norma Nowak, one of the leaders involved with the Genomic Medicine Initiative.

The study of the human genome — the complete set of genetic information for human beings — is perhaps the largest collaborative research project ever undertaken.

Partners at UB’s New York State Center of Excellence in Bioinformatics & Life Sciences (CBLS) have been key contributors to this endeavor.

Learn more

Visit the UB Genomics & Bioinformatics Core website for a complete list of equipment, services and staff.

Developmental genomics

The Developmental Genomics group studies and analyzes gene expression patterns and genetic perturbations of model organisms to better understand the developmental processes of organisms and diseases.

Nationally recognized experts and next-generation facilities

The powerful combination of our nationally recognized UB faculty and staff, state-of-the-art equipment and high-performance computing resources is helping establish Buffalo Niagara as a national leader in genome research. Through this leadership, the CBLS will help usher in a new era of medicine.

The UB Genomics & Bioinformatics Core is the area’s first sequencing service provider and offers a wide range of genomic and epigenomic services on multiple platforms.

The core is located within the CBLS, and currently offers services on the following analysis platforms:

High-Throughput Sequencing

  • illumina HiSeq2500
  • Life Technologies' Ion PGM
  • Life Technologies' Ion Proton

 Additional Genomic Technology Platforms and Services

  • Affymetrix Genechip System
  • Diagenode SX-8G Compact Automated Systems
  • QX100 Droplet Digital PCR machine (Biorad)
  • Agilent Microarray Scanner G2505C

Director

Norma J. Nowak, PhD
Director of Science and Technology
New York State Center of Excellence in Bioinformatics & Life Sciences
716 881 8903
njnowak@buffalo.edu

Norma Jean Nowak, PhD, is recognized as a leader in the field of human genomics. Her research contributed directly to the Human Genome Project, as well as to microarray-based approaches to understanding heritable disorders and cancer. In addition to her leadership role at the CBLS, Dr. Nowak is the founder and chief scientific officer of Empire Genomics LLC, a molecular diagnostics firm focused on enabling personalized medicine.

Among her major achievements, Nowak has authored landmark papers describing the cloning of several heritable cancer disorders, and her work on the Human Genome Project was published in the genome issue of Nature. Dr. Nowak also led and coordinated the three groups for the National Cancer Institute’s extramural Cancer Chromosome Aberration Project, and was a key member of the GENSAT project. She has authored or co-authored more than 140 research articles in leading scientific journals, has served as an associate editor of Physiological Genomics, and is currently on the editorial board of Cytogenetic and Genome Research as an associate editor.

For more information about UB's Genomics & Bioinformatics Core, please contact:

Sujith Valiyaparambil
Research Associate
716 881 7514
alphy@buffalo.edu

 

Faculty investigators

Norma J. Nowak, PhD

Professor

Department of Biochemistry

Center of Excellence in Bioinformatics & Life Sciences, 701 Ellicott St., Room B2-201, Buffalo, NY 14203

Phone: 716.881.8903; 716.845.1698

Email: njnowak@buffalo.edu

Richard M. Gronostajski, PhD

Professor of Biochemistry; Director of the Genetics, Genomics & Bioinformatics Graduate Program; Director, Western New York Stem Cell Culture and Analysis Center (WNYSTEM)

Department of Biochemistry

Center of Excellence in Bioinformatics & Life Sciences, 701 Ellicott St., Room 3-303, Buffalo, NY 14203

Phone: 716.829.3471

Email: rgron@buffalo.edu

Satrajit Sinha, PhD

Associate Professor

Department of Biochemistry

Center Of Excellence in Bioinformatics & Life Sciences, 701 Ellicott St., Buffalo, NY 14203

Phone: 716.881.7994

Email: ssinha2@buffalo.edu

Marc S. Halfon, PhD

Associate Professor

Department of Biochemistry

Center of Excellence in Bioinformatics & Life Sciences, 701 Ellicott St., B3-307, Buffalo, NY 14203

Phone: 716.829.3126

Email: mshalfon@buffalo.edu

Michael Buck, PhD

Assistant Professor

Department of Biochemistry

Center Of Excellence in Bioinformatics & Life Sciences, 701 Ellicott St., Room B3-304, Buffalo, NY 14203

Phone: 716.881.7569

Email: mjbuck@buffalo.edu

Lee Ann Garrett-Sinha, PhD

Associate Professor

Department of Biochemistry

Center of Excellence in Bioinformatics & Life Sciences, 701 Ellicott St., B3-306, Buffalo, NY 14203

Phone: 716.881.7995

Email: leesinha@buffalo.edu

Xiuqian Mu, PhD

Assistant Professor

Department of Ophthalmology

Center of Excellence in Bioinformatics & Life Sciences, 701 Ellicott St., Rm B4-307, Buffalo, NY 14203

Phone: 716.881.7463

Email: xmu@buffalo.edu